Gene Report

Basic Info
Approved Symbol KLHDC1
Symbol Alias MST025
Approved Name kelch domain containing 1
Location 14q21.3
Position chr14:49693105-49753152, 1
External Links HGNC: 19836
Entrez Gene: 122773
Ensembl: ENSG00000197776
UCSC: uc001www.3
No. of Studies 2 (Positive: 1; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Feng, T.,2010 SNP: rs10149544 This gene showed moderate association evidence. Trend Comment on Study
Moskvina, V.,2009 In BP:Smallest P-value per gene=0.00017, Product of P truncation <=0.01=0.00015, Product of P truncation <=0.001=0.00015. It showed evidence for association with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 1)

GO terms by PBA (count: 0)

GO terms by database search (count: 1)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr14:49693105..49753152 View in gBrowse
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