BDgene

Gene Report

Basic Info
Approved Symbol MYL12B
Symbol Alias MRLC2
Approved Name myosin, light chain 12B, regulatory
Name Alias myosin regulatory light chain 2
Location 18p11.31
Position chr18:3261909-3278284, 1
External Links HGNC: 29827
Entrez Gene: 103910
Ensembl: ENSG00000118680
UCSC: uc002klt.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Moskvina, V.,2009 In BD:Smallest P-value per gene=0.00246, Product of P truncation <=0.01=0.01078, Product of P truncation <=0.001=0.00246. It showed evidence for association with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 2)

GO terms by database search (count: 10)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 7)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)


Gene relationship with MDD

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Region: chr18:3261909..3278284 View in gBrowse
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