Gene Report

Basic Info
Approved Symbol ZNF274
Symbol Alias ZKSCAN19, ZSCAN51
Approved Name zinc finger protein 274
Location 19q13.43
Position chr19:58183029-58213562, 1
External Links HGNC: 13068
Entrez Gene: 10782
Ensembl: ENSG00000171606
UCSC: uc032igq.1
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Moskvina, V.,2009 In BP:Smallest P-value per gene=0.00005, Product of P truncation <=0.01=0.00005, Product of P truncation <=0.001=0.00005. It showed evidence for association with BD. Positive Comment on Study
Xu, W., 2014 SNP: rs4444432, rs7256349 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 4)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 9)

Literature-origin SNPs (count: 4)

LD-proxies (count: 5)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr19:58183029..58213562 View in gBrowse
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