Region Report

Basic Info

Region Name	Chr 11
Chromosome Position	chr11:0-135086622
No. of Studies (Positive/Negative/Trend)	2(0/2/0)

Region related studies (count: 2)

Reference	Markers	Statistical Values	Author Comments	Result Category
Murphy, V. E.,2000	D11S1346	Linkage analysis: broad model, NPL = 0.378, P-value = 0.34; ...... Linkage analysis: broad model, NPL = 0.378, P-value = 0.34; narrow model, NPL = -0.207, P-value = 0.63 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Badner, J. A.,2002		Meta analysis: Location: 66, Single Analysis MSP = 0.01, Bes...... Meta analysis: Location: 66, Single Analysis MSP = 0.01, Best Analysis MSP = 0.03 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 50)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DLG2	discs, large homolog 2 (Drosophila)	11q21	3(1/1/1)
CRY2	cryptochrome circadian clock 2	11p11.2	5(3/2/0)
CHRM4	cholinergic receptor, muscarinic 4	11p12-p11.2	1(0/1/0)
ADM	adrenomedullin	11p15.4	1(1/0/0)
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	11p13-p12	1(1/0/0)
DRD2	dopamine receptor D2	11q22-q23	28(8/20/0)
TH	tyrosine hydroxylase	11p15.5	16(4/12/0)
FAM118B	family with sequence similarity 118, member B	11q24.2	1(1/0/0)
DRD4	dopamine receptor D4	11p15.5	13(1/12/0)
NRXN2	neurexin 2	11q13	1(1/0/0)
SLC5A12	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12	11p14.2	1(1/0/0)
NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2	11q14.3-q21	1(0/1/0)
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	11q13.3	1(1/0/0)
CHRNA10	cholinergic receptor, nicotinic, alpha 10 (neuronal)	11p15.5	1(0/1/0)
ZDHHC13	zinc finger, DHHC-type containing 13	11p15.1	1(0/0/1)
NAV2	neuron navigator 2	11p15.1	1(1/0/0)
CCKBR	cholecystokinin B receptor	11p15.4	1(1/0/0)
NNMT	nicotinamide N-methyltransferase	11q23.1	1(1/0/0)
ALG9	ALG9, alpha-1,2-mannosyltransferase	11q23	1(0/1/0)
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	11p15.4	1(0/1/0)
GRIK4	glutamate receptor, ionotropic, kainate 4	11q23.3	2(1/1/0)
CARD16	caspase recruitment domain family, member 16	11q23	1(0/0/1)
ANO3	anoctamin 3	11p14.2	1(1/0/0)
ALKBH8	alkB, alkylation repair homolog 8 (E. coli)	11q22.3	1(0/1/0)
MMP3	matrix metallopeptidase 3	11q22.3	1(0/1/0)
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	11q23.1-q23.2	2(1/1/0)
PIK3C2A	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	11p15.5-p14	1(0/1/0)
SHANK2	SH3 and multiple ankyrin repeat domains 2	11q13.2	2(1/1/0)
BDNF	brain-derived neurotrophic factor	11p14.1	37(24/12/1)
TENM4	teneurin transmembrane protein 4	11q13	6(4/2/0)
TYR	tyrosinase	11q14.3	1(0/1/0)
KAT5	K(lysine) acetyltransferase 5	11q13	2(0/2/0)
SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 5	11p15.1	1(0/1/0)
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	11q24.2	2(0/2/0)
CHRM1	cholinergic receptor, muscarinic 1	11q12-q13	1(0/1/0)
OR5AS1	olfactory receptor, family 5, subfamily AS, member 1	11q11	1(0/0/1)
NRGN	neurogranin (protein kinase C substrate, RC3)	11q24	2(1/1/0)
NCAM1	neural cell adhesion molecule 1	11q23.2	3(2/1/0)
NCAPD3	non-SMC condensin II complex, subunit D3	11q25	1(1/0/0)
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)
TPH1	tryptophan hydroxylase 1	11p15.3-p14	14(5/9/0)
TPP1	tripeptidyl peptidase I	11p15.4	1(1/0/0)
HTR3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	11q23.1	2(1/1/0)
OR4X2	olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)	11p11.2	1(0/0/1)
CTTN	cortactin	11q13	1(1/0/0)
OPCML	opioid binding protein/cell adhesion molecule-like	11q25	1(0/1/0)
JAM3	junctional adhesion molecule 3	11q25	2(1/1/0)
CASP1	caspase 1, apoptosis-related cysteine peptidase	11q23	1(0/0/1)
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	11q11-q12	1(1/0/0)
INS	insulin	11p15.5	1(0/1/0)

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Region: chr11:0..135086622 View in gBrowse