Gene Report

Basic Info
Approved Symbol CASP1
Previous Symbol IL1BC
Symbol Alias ICE
Approved Name caspase 1, apoptosis-related cysteine peptidase
Previous Name caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase), "caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)"
Name Alias caspase-1, "interleukin 1, beta, convertase"
Location 11q23
Position chr11:105025443-105035250, -1
External Links HGNC: 1499
Entrez Gene: 834
Ensembl: ENSG00000137752
UCSC: uc001pim.5
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Cruceanu, C., 2013 Other variant: CASP1_Chr11:104901923 Rare variant was found within this gene. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 35)

GO terms by PBA (count: 2)

GO terms by database search (count: 33)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 3)

Gene related BioCarta pathways (count: 3)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 3)

Gene related interactors from protein-protein interactions data in HPRD (count: 35)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr11:105025443..105035250 View in gBrowse
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