Region Report

Basic Info

Region Name	Chr 5
Chromosome Position	chr5:0-181538259
No. of Studies (Positive/Negative/Trend)	3(0/2/1)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
Dick, D. M.,2002		Linkage analysis: Model 2, Affected relative pairs LOD = 1.6...... Linkage analysis: Model 2, Affected relative pairs LOD = 1.64, Location 157cM; Affected sibling pairs: sib IBD LOD = 1.89, Location 150cM, sib Phase LOD = 1.23, Location 150cM; Model 3, Affected relative pairs LOD = 1.69, Location 157cM; Affected sibling pairs: sib IBD LOD = 2.83, Location 150cM, sib Phase LOD = 1.03, Location 150cM More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Murphy, V. E.,2000	D5S668	Linkage analysis: broad model, NPL = -0.345, P-value = 0.64;...... Linkage analysis: broad model, NPL = -0.345, P-value = 0.64; narrow model, NPL = 0.459, P-value = 0.21 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Badner, J. A.,2002		Meta analysis: Location: 200, Single Analysis MSP = 0.2, Bes...... Meta analysis: Location: 200, Single Analysis MSP = 0.2, Best Analysis MSP = 0.1 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 57)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLU7	SLU7 splicing factor homolog (S. cerevisiae)	5q33.3	1(0/0/1)
BASP1	brain abundant, membrane attached signal protein 1	5p15.1	1(0/0/1)
ADCY2	adenylate cyclase 2 (brain)	5p15.3	2(1/1/0)
WWC1	WW and C2 domain containing 1	5q34	1(0/0/1)
ADRA1B	adrenoceptor alpha 1B	5q33.3	1(1/0/0)
TENM2	teneurin transmembrane protein 2	5q35	1(0/0/1)
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	5q13.1	1(1/0/0)
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)
RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2	5q13	1(0/0/1)
GABRA6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	5q34	1(0/1/0)
GDNF	glial cell derived neurotrophic factor	5p13.1-p12	1(1/0/0)
DIAPH1	diaphanous-related formin 1	5q31	1(1/0/0)
GLRA1	glycine receptor, alpha 1	5q33.1	1(1/0/0)
PDE4D	phosphodiesterase 4D, cAMP-specific	5q12	1(0/1/0)
ADRB2	adrenoceptor beta 2, surface	5q31-q32	1(1/0/0)
EGR1	early growth response 1	5q23-q31	1(0/1/0)
GPX3	glutathione peroxidase 3	5q33.1	1(1/0/0)
LSM11	LSM11, U7 small nuclear RNA associated	5q33.3	1(1/0/0)
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	5q32	2(1/1/0)
NMUR2	neuromedin U receptor 2	5q33.1	1(0/1/0)
NIPBL	Nipped-B homolog (Drosophila)	5p13.2	1(0/1/0)
AHRR	aryl-hydrocarbon receptor repressor	5p15.33	1(1/0/0)
EXOC3-AS1	EXOC3 antisense RNA 1	5p15.33	1(1/0/0)
PLCXD3	phosphatidylinositol-specific phospholipase C, X domain containing 3	5p13.1	1(1/0/0)
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	5q34	1(1/0/0)
CRHBP	corticotropin releasing hormone binding protein	5q13.3	1(0/1/0)
SLIT3	slit homolog 3 (Drosophila)	5q35	1(1/0/0)
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	5q34	2(1/1/0)
DRD1	dopamine receptor D1	5q34-q35	11(6/5/0)
CEP72	centrosomal protein 72kDa	5p15.33	1(1/0/0)
CCDC69	coiled-coil domain containing 69	5q33.1	1(1/0/0)
HTR4	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	5q31-q33	2(1/1/0)
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	5p15.2	1(1/0/0)
HARS	histidyl-tRNA synthetase	5q31.3	1(0/1/0)
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	5q31-q32	5(2/3/0)
CTNND2	catenin (cadherin-associated protein), delta 2	5p15.2	1(0/1/0)
TRIO	trio Rho guanine nucleotide exchange factor	5p14-p15.1	1(0/1/0)
PRLR	prolactin receptor	5p14-p13	1(1/0/0)
OR2Y1	olfactory receptor, family 2, subfamily Y, member 1	5q35	1(0/0/1)
FST	follistatin	5q11.2	1(0/0/1)
SNX24	sorting nexin 24	5q23.2	1(1/0/0)
ITK	IL2-inducible T-cell kinase	5q31-q32	1(1/0/0)
PRR16	proline rich 16	5q23.1	1(0/1/0)
GRIA1	glutamate receptor, ionotropic, AMPA 1	5q33	2(2/0/0)
SRD5A1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	5p15.31	1(1/0/0)
PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	5q33.1	1(1/0/0)
EXOC3	exocyst complex component 3	5p15.33	1(1/0/0)
FBXO38	F-box protein 38	5q33.1	2(1/0/1)
CARTPT	CART prepropeptide	5q13.2	1(0/1/0)
LINC00992	long intergenic non-protein coding RNA 992	5q23.1	1(0/1/0)
FSTL4	follistatin-like 4	5q31.1	1(0/0/1)
EBF1	early B-cell factor 1	5q34	1(1/0/0)
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	5q14.2	1(0/1/0)
SLC9A3	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	5p15.3	1(1/0/0)
PCDHA@	protocadherin alpha cluster, complex locus	5q31	2(1/1/0)
OXCT1	3-oxoacid CoA transferase 1	5p13	1(1/0/0)
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	5q11.2-q13	3(2/1/0)

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Region: chr5:0..181538259 View in gBrowse