Gene Report

Basic Info
Approved Symbol WWC1
Symbol Alias KIBRA, KIAA0869, PPP1R168
Approved Name WW and C2 domain containing 1
Previous Name WW, C2 and coiled-coil domain containing 1
Name Alias protein phosphatase 1, regulatory subunit 168
Location 5q34
Position chr5:168291651-168472303, 1
External Links HGNC: 29435
Entrez Gene: 23286
Ensembl: ENSG00000113645
UCSC: uc011den.2
No. of Studies 1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Cruceanu, C., 2013 Other variant: WWC1_Chr5:167896045_G/A Rare variant was found within this gene. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 21)

GO terms by PBA (count: 2)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr5:168291651..168472303 View in gBrowse
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