Gene Report

Basic Info
Approved Symbol SLIT3
Previous Symbol SLIL2
Symbol Alias slit2, MEGF5, SLIT1, Slit-3
Approved Name slit homolog 3 (Drosophila)
Previous Name slit (Drosophila) homolog 3
Location 5q35
Position chr5:168661733-169301129, -1
External Links HGNC: 11087
Entrez Gene: 6586
Ensembl: ENSG00000184347
UCSC: uc010jjg.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0011. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 17)

GO terms by PBA (count: 2)

GO terms by database search (count: 15)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr5:168661733..169301129 View in gBrowse
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