Gene Report

Basic Info
Approved Symbol ADRB2
Previous Symbol ADRB2R
Symbol Alias ADRBR, BAR, B2AR
Approved Name adrenoceptor beta 2, surface
Previous Name adrenergic, beta-2-, receptor, surface
Location 5q31-q32
Position chr5:148825245-148828687, 1
External Links HGNC: 286
Entrez Gene: 154
Ensembl: ENSG00000169252
UCSC: uc003lpr.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Dizier, M. H.,2012 Gene-based approach:Empirical P-value = 0.003(EAAO versus HC); Empirical P-value = 0.81(LAAO versus HC); ADRB2 (beta-2adrenoreceptor) gene region that is specifically associated with the early onset form of BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 37)

GO terms by PBA (count: 5)

GO terms by database search (count: 32)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 2)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 2)

Gene related interactors from protein-protein interactions data in HPRD (count: 23)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:148825245..148828687 View in gBrowse
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