Gene Report

Basic Info
Approved Symbol GLRA1
Previous Symbol STHE
Approved Name glycine receptor, alpha 1
Previous Name glycine receptor, alpha 1 (startle disease/hyperekplexia)
Name Alias startle disease/hyperekplexia, "stiff person syndrome"
Location 5q33.1
Position chr5:151822513-151924842, -1
External Links HGNC: 4326
Entrez Gene: 2741
Ensembl: ENSG00000145888
UCSC: uc003lut.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Gratacos, M.,2009 SNP: rs2071220 Nominal associations with bipolar disorder was observed. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 34)

GO terms by PBA (count: 5)

GO terms by database search (count: 29)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 8)

Literature-origin SNPs (count: 1)

LD-proxies (count: 7)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:151822513..151924842 View in gBrowse
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