Gene Report

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Basic Info

Approved Symbol	SNX24
Symbol Alias	SBBI31
Approved Name	sorting nexin 24
Location	5q23.2
Position	chr5:122843439-123029354, 1
External Links	HGNC: 21533 Entrez Gene: 28966 Ensembl: ENSG00000064652 UCSC: uc011cwo.2
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Noor A., 2014		Selected stringent CNV related to this gene is validated by qPCR from BD case data.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0015031	protein transport	biological process	IEA	21
GO:0035091	phosphatidylinositol binding	molecular function	IEA	5
GO:0030659	cytoplasmic vesicle membrane	cellular component	IEA	12

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
SNX24	SH3GL3	NO	yeast 2-hybrid	16169070

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Abdul Noor[2014]_8	chr5:122197444-122353529 (NCBI Build 36/hg18)	156000	5q23.2	duplication

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 5	chr5:0-181538259	3 (0/2/1)
5q14.3-q23.3	chr5:83500000-131200000	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:122843439..123029354 View in gBrowse