BDgene

Gene Report

Basic Info
Approved Symbol TRIO
Symbol Alias ARHGEF23
Approved Name trio Rho guanine nucleotide exchange factor
Previous Name triple functional domain (PTPRF interacting)
Location 5p14-p15.1
Position chr5:14143702-14532128, 1
External Links HGNC: 12303
Entrez Gene: 7204
Ensembl: ENSG00000038382
UCSC: uc003jff.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs16903467 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 16)

GO terms by PBA (count: 4)

GO terms by database search (count: 12)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)


Gene related interactors from protein-protein interactions data in HPRD (count: 5)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)


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Region: chr5:14143702..14532128 View in gBrowse
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