GO Report

Basic Info
ID GO:0007399
Name nervous system development
Type biological process
No. of Genes in BDgene  40
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
GO: 0007399: nervous system development PBA paper Askland, K.,2009 NIMH Fisher's exact test Results given for gene sets with P < 0.01 from the NIMH PBA-BP data

GO related genes in BDgene (count: 40)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
ERBB4 erb-b2 receptor tyrosine kinase 4 2q33.3-q34 2(1/1/0) ISS
TPP1 tripeptidyl peptidase I 11p15.4 1(1/0/0) IMP[9295267]
MBNL1 muscleblind-like splicing regulator 1 3q25 1(1/0/0) ISS
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 7q21.11 1(1/0/0) IEA
NR2E1 nuclear receptor subfamily 2, group E, member 1 6q21 1(1/0/0) TAS[9628820]
DLG3 discs, large homolog 3 (Drosophila) Xq13.1 1(0/1/0) IBA
ARID1B AT rich interactive domain 1B (SWI1-like) 6q25.3 1(0/0/1) IEA
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 20q13.33 1(1/0/0) TAS[9425895]
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 5p15.2 1(1/0/0) TAS[9464278]
DSCAM Down syndrome cell adhesion molecule 21q22.2-q22.3 3(1/2/0) TAS[9426258]
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2p21 1(0/1/0) TAS[10642437]
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 11q24.2 2(0/2/0) TAS[9096408]
FABP7 fatty acid binding protein 7, brain 6q22-q23 1(1/0/0) TAS[9375786]
MYT1L myelin transcription factor 1-like 2p25.3 1(1/0/0) IEA
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18p11.22 6(5/1/0) IMP[9570948]
GDNF glial cell derived neurotrophic factor 5p13.1-p12 1(1/0/0) TAS[8637574]
NRG1 neuregulin 1 8p12 15(10/5/0) TAS[17432114]
CNTN4 contactin 4 3p26.3 1(1/0/0) IMP[15106122]
DLG1 discs, large homolog 1 (Drosophila) 3q29 2(1/1/0) IBA
TSHR thyroid stimulating hormone receptor 14q24-q31 1(1/0/0) IBA
DOK5 docking protein 5 20q13.2 1(1/0/0) IEA
APOB apolipoprotein B 2p24-p23 1(0/0/1) IEA
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1q43 2(1/1/0) TAS[8968737]
HES1 hes family bHLH transcription factor 1 3q28-q29 1(0/1/0) TAS[8020957]
FGF12 fibroblast growth factor 12 3q28 1(0/1/0) TAS[8790420]
GSS glutathione synthetase 20q11.2 1(0/0/1) TAS[8896573]
SCN8A sodium channel, voltage gated, type VIII alpha subunit 12q13.1 1(1/0/0) TAS[9828131]
CHRM1 cholinergic receptor, muscarinic 1 11q12-q13 1(0/1/0) TAS[2739737]
OLFM1 olfactomedin 1 9q34.3 1(1/0/0) TAS[9039501]
CHRM3 cholinergic receptor, muscarinic 3 1q43 1(0/1/0) TAS[2739737]
LGI1 leucine-rich, glioma inactivated 1 10q24 1(0/1/0) TAS[9879993]
DGCR14 DiGeorge syndrome critical region gene 14 22q11.21 1(0/1/0) ISS[8703114]
CHRM2 cholinergic receptor, muscarinic 2 7q35-q36 1(0/1/0) TAS[2739737]
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15q26 2(2/0/0) TAS[9054414]
DPYSL2 dihydropyrimidinase-like 2 8p22-p21 2(1/0/1) TAS[8973361]
NRGN neurogranin (protein kinase C substrate, RC3) 11q24 2(1/1/0) TAS[10075657]
BDNF brain-derived neurotrophic factor 11p14.1 37(24/12/1) TAS[2236018]
DLG2 discs, large homolog 2 (Drosophila) 11q21 3(1/1/1) IBA
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 6p21.1 1(1/0/0) TAS[8703017]
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 3(1/2/0) IMP[11450844]