Gene Report

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Basic Info

Approved Symbol	OLFM1
Symbol Alias	NOE1, OlfA, AMY, NOELIN
Approved Name	olfactomedin 1
Name Alias	pancortin
Location	9q34.3
Position	chr9:135075422-135121179, 1
External Links	HGNC: 17187 Entrez Gene: 10439 Ensembl: ENSG00000130558 UCSC: uc010nar.4
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0021. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0045202	synapse	cellular component	IEA	29
GO:0007399	nervous system development	biological process	TAS[9039501]	40

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:1902430	negative regulation of beta-amyloid formation	biological process	IEA	2
GO:0010718	positive regulation of epithelial to mesenchymal transition	biological process	ISS	2
GO:0010628	positive regulation of gene expression	biological process	ISS	23
GO:0005515	protein binding	molecular function	IPI[17043677]	563
GO:0060317	cardiac epithelial to mesenchymal transition	biological process	ISS	2
GO:0001540	beta-amyloid binding	molecular function	IEA	4
GO:0005615	extracellular space	cellular component	IEA	85
GO:0010629	negative regulation of gene expression	biological process	ISS	12
GO:0051259	protein oligomerization	biological process	IEA	7
GO:0030054	cell junction	cellular component	IEA	88
GO:0005623	cell	cellular component	ISS	2
GO:0032281	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex	cellular component	IEA	8
GO:0003190	atrioventricular valve formation	biological process	ISS	1
GO:2001223	negative regulation of neuron migration	biological process	IEA	2

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 9	chr9:0-138394717	3 (0/3/0)
9q33.3-34.3	chr9:123100000-138394717	1 (0/1/0)
9q34	chr9:127500000-138394717	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr9:135075422..135121179 View in gBrowse