Region Report

Basic Info

Region Name	Chr 14
Chromosome Position	chr14:0-107043718
No. of Studies (Positive/Negative/Trend)	2(0/2/0)

Region related studies (count: 2)

Reference	Markers	Statistical Values	Author Comments	Result Category
Murphy, V. E.,2000	D14S281	Linkage analysis: broad model, NPL = -0.043, P-value = 0.52;...... Linkage analysis: broad model, NPL = -0.043, P-value = 0.52; narrow model, NPL = 0.222, P-value = 0.37 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Avramopoulos, D., 2007	D14S288 (BPI, BPII & BPI, restricted)	P-value = 0.07, NPL = 1.47, Dominant Max HLOD = 0.49, Rec...... P-value = 0.07, NPL = 1.47, Dominant Max HLOD = 0.49, Recessive Max HLOD = 0.68 in Ashkenazi pedigrees; P-value = 0.06, NPL = 1.57, Dominant Max HLOD = 0.52, Recessive Max HLOD = 0.89 in BPI-restricted pedigrees More...	the absolute value of the resulting scores remained moderate the absolute value of the resulting scores remained moderate	Negative

Region related genes (count: 51)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
FLVCR2	feline leukemia virus subgroup C cellular receptor family, member 2	14q24.3	1(1/0/0)
KLHDC1	kelch domain containing 1	14q21.3	2(1/0/1)
PTGR2	prostaglandin reductase 2	14q24.1-q24.2	1(1/0/0)
MIR2392	microRNA 2392	14	1(0/1/0)
ZFYVE21	zinc finger, FYVE domain containing 21	14q32.33	1(0/1/0)
NUMB	numb homolog (Drosophila)	14q24.3	1(0/0/1)
RNASE4	ribonuclease, RNase A family, 4	14q11	1(0/1/0)
LRRC74A	leucine rich repeat containing 74A	14q24.3	1(0/1/0)
AKT1	v-akt murine thymoma viral oncogene homolog 1	14q32.33	3(3/0/0)
C14orf166B	leucine rich repeat containing 74A	14q24.3	0
NRXN3	neurexin 3	14q31	2(2/0/0)
GSTZ1	glutathione S-transferase zeta 1	14q24.3	1(1/0/0)
C14orf80	chromosome 14 open reading frame 80	14q32.33	1(0/1/0)
GEMIN2	gem (nuclear organelle) associated protein 2	14q21.1	1(0/1/0)
BDKRB1	bradykinin receptor B1	14q32.1-q32.2	1(1/0/0)
MIPOL1	mirror-image polydactyly 1	14q13.3	1(0/0/1)
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	14q32.31	1(0/1/0)
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	14q32.32	1(0/1/0)
GCH1	GTP cyclohydrolase 1	14q22.1-q22.2	2(1/1/0)
DIO3	deiodinase, iodothyronine, type III	14q32	1(0/1/0)
KCNK10	potassium channel, two pore domain subfamily K, member 10	14q31	1(1/0/0)
SERPINA12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	14q32.13	1(1/0/0)
ADSSL1	adenylosuccinate synthase like 1	14q32.33	1(0/1/0)
TRIM9	tripartite motif containing 9	14q21.3	1(0/1/0)
KIF26A	kinesin family member 26A	14q32.33	1(0/1/0)
DIO2	deiodinase, iodothyronine, type II	14q24.2-q24.3	1(1/0/0)
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	14q24	2(1/1/0)
FOXN3	forkhead box N3	14q32.11	1(1/0/0)
RCOR1	REST corepressor 1	14q32.33	1(0/1/0)
CEP170B	centrosomal protein 170B	14q32.33	1(0/1/0)
SSTR1	somatostatin receptor 1	14q13	1(1/0/0)
POLE2	polymerase (DNA directed), epsilon 2, accessory subunit	14q21-q22	1(1/0/0)
TSHR	thyroid stimulating hormone receptor	14q24-q31	1(1/0/0)
IGH	immunoglobulin heavy locus	14q32.33	1(0/1/0)
CMA1	chymase 1, mast cell	14q12	1(0/0/1)
TDRD9	tudor domain containing 9	14q32.33	3(1/1/1)
SLC25A21	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21	14q13.3	1(0/0/1)
RBM23	RNA binding motif protein 23	14q11.1	1(0/1/0)
NPAS3	neuronal PAS domain protein 3	14q13.1	2(1/1/0)
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	14q32.31	1(0/1/0)
RAD51B	RAD51 paralog B	14q23-q24.2	1(0/1/0)
LRR1	leucine rich repeat protein 1	14q21.3	1(1/0/0)
CGRRF1	cell growth regulator with ring finger domain 1	14q22.2	1(0/1/0)
OTX2	orthodenticle homeobox 2	14q22.3	1(1/0/0)
BDKRB2	bradykinin receptor B2	14q32.1-q32.2	1(1/0/0)
YY1	YY1 transcription factor	14q	1(0/1/0)
SERPINA11	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	14q32.13	1(1/0/0)
SIVA1	SIVA1, apoptosis-inducing factor	14q32.33	1(0/1/0)
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14q32.33	1(1/0/0)
SNORD114-7	small nucleolar RNA, C/D box 114-7	14q32.31	1(0/1/0)
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	14q11.2	1(0/1/0)

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Region: chr14:0..107043718 View in gBrowse