Gene Report

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Basic Info

Approved Symbol	MIPOL1
Approved Name	mirror-image polydactyly 1
Location	14q13.3
Position	chr14:37197913-37552361, 1
External Links	HGNC: 21460 Entrez Gene: 145282 Ensembl: ENSG00000151338 UCSC: uc001wuc.3
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Jamain, S., 2014	SNP: rs8019549, rs10135285	It showed nominal evidence for association with BD.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 2)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005634	nucleus	cellular component	IDA[19667180]	283

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005515	protein binding	molecular function	IPI[25416956]	563

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs10135285	chr14:37218635 - 37218635(1)	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1(0/0/1)
rs8019549	chr14:37227774 - 37227774(1)	5_prime_UTR_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
14q13.2-21.3	chr14:34800000-50400000	1 (0/1/0)
Chr 14	chr14:0-107043718	2 (0/2/0)
14q12-q22.3	chr14:24100000-57600000	1 (1/0/0)
14q13.1-21.1	chr14:32900000-43000000	1 (0/1/0)
14q13.1-q24.1	chr14:32900000-69800000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:37197913..37552361 View in gBrowse