Gene Report

Basic Info
Approved Symbol KCNK10
Symbol Alias K2p10.1, TREK-2, TREK2, PPP1R97
Approved Name potassium channel, two pore domain subfamily K, member 10
Previous Name potassium channel, subfamily K, member 10
Name Alias protein phosphatase 1, regulatory subunit 97
Location 14q31
Position chr14:88180103-88326907, -1
External Links HGNC: 6273
Entrez Gene: 54207
Ensembl: ENSG00000100433
UCSC: uc001xwn.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0018. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 11)

GO terms by PBA (count: 5)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:88180103..88326907 View in gBrowse
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