GO Report

Basic Info

ID	GO:0005102
Name	receptor binding
Type	molecular function
No. of Genes in BDgene	37
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
GO:05102 : receptor binding	PBA paper	Holmans, P., 2009	WTCCC+STEP-UCL+ED-DUB-STEP2	ALIGATOR (Association LIst Go AnnoTatOR)	FUNCTION, cutoff for significant SNPs: p < 0.01

GO related genes in BDgene (count: 37)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
HLA-A	major histocompatibility complex, class I, A	6p21.3	1(0/1/0)	IBA; IPI[19124746]
ADM	adrenomedullin	11p15.4	1(1/0/0)	TAS[8074714]
GDNF	glial cell derived neurotrophic factor	5p13.1-p12	1(1/0/0)	TAS[10829012]
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	18p11	3(1/2/0)	IPI[7680413]
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)	IEA
TENM2	teneurin transmembrane protein 2	5q35	1(0/0/1)	IDA[21724987]; IEA
CRH	corticotropin releasing hormone	8q13	2(1/1/0)	TAS[7477348]
NPPB	natriuretic peptide B	1p36.2	1(1/0/0)	IDA[1672777]; IPI[12727915]
HNF4A	hepatocyte nuclear factor 4, alpha	20q13.12	1(1/0/0)	IDA[12220494]
LGI1	leucine-rich, glioma inactivated 1	10q24	1(0/1/0)	IPI[20463223]; IPI[20463223]
LAMA3	laminin, alpha 3	18q11.2	1(0/0/1)	IEA
HLA-G	major histocompatibility complex, class I, G	6p21.3	1(1/0/0)	IPI[20702625]
DIAPH1	diaphanous-related formin 1	5q31	1(1/0/0)	NAS[9360932]
GJA1	gap junction protein, alpha 1, 43kDa	6q22.31	1(1/0/0)	IEA
HLA-B	major histocompatibility complex, class I, B	6p21.3	2(0/1/1)	IBA; IPI[20008523]
NRXN1	neurexin 1	2p16.3	1(1/0/0)	ISS
ITK	IL2-inducible T-cell kinase	5q31-q32	1(1/0/0)	IBA
CXCL12	chemokine (C-X-C motif) ligand 12	10q11.1	1(0/0/1)	TAS[10358157]
GFRA1	GDNF family receptor alpha 1	10q25-q26	2(1/1/0)	TAS[9545641]
PTPRD	protein tyrosine phosphatase, receptor type, D	9p24.1-p23	1(0/0/1)	ISS
ANXA1	annexin A1	9q21.13	1(0/0/1)	TAS[10882119]
DDO	D-aspartate oxidase	6q22.1	1(1/0/0)	IPI[20178365]
P2RX4	purinergic receptor P2X, ligand gated ion channel, 4	12q24.32	1(0/1/0)	ISS[17785580]
CROT	carnitine O-octanoyltransferase	7q21.1	1(0/0/1)	IPI[20178365]
PLA2G1B	phospholipase A2, group IB (pancreas)	12q24.31	4(1/3/0)	IDA[1918029]; IPI[7721806]
CD276	CD276 molecule	15q23-q24	1(0/1/0)	NAS[11224528]
ARRB2	arrestin, beta 2	17p13	1(1/0/0)	IPI[18604210]
UFD1L	ubiquitin fusion degradation 1 like (yeast)	22q11.2	1(0/1/0)	IEA
CHRNA10	cholinergic receptor, nicotinic, alpha 10 (neuronal)	11p15.5	1(0/1/0)	TAS[11350119]
ITGB8	integrin, beta 8	7p15.3	1(1/0/0)	IEA
DAO	D-amino-acid oxidase	12q24.11	5(1/4/0)	IPI[20178365]
CCL2	chemokine (C-C motif) ligand 2	17q11.2-q21.1	3(1/2/0)	TAS[10542238]
PICK1	protein interacting with PRKCA 1	22q13.1	1(0/1/0)	ISS
NRG3	neuregulin 3	10q23.1	2(0/2/0)	IBA
TRIM24	tripartite motif containing 24	7q32-q34	1(1/0/0)	TAS[9115274]
P2RX7	purinergic receptor P2X, ligand gated ion channel, 7	12q24	9(2/7/0)	ISS[17785580]
NRG1	neuregulin 1	8p12	15(10/5/0)	IPI[7514177]