BDgene

Region Report

Basic Info
Region Name 12q
Chromosome Position chr12:38200000-133851895
No. of Studies (Positive/Negative/Trend)  1(1/0/0)

Region related studies (count: 1)
Reference Markers Statistical Values Author Comments Result Category
Dawson, E.,1995 D12S342 - D12S76 - PLA2A - D12S79 -D12S84 - D12S78 - D12S101 Allele 122 bp was more common in controls (X2 = ...... Allele 122 bp was more common in controls (X2 = 8.85, df = 1, P-value = 0.003) and allele 134 bp was more common in cases (X2 = 5.62, df = 1, P-value = 0.02). Of the 7 markers , PLA2A shows significant association with bipolar disorder. More... PLA2A shows significant association with bipolar disorder in...... PLA2A shows significant association with bipolar disorder in this region More... Positive

Region related genes (count: 50)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 12q24.11 2(0/2/0)
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 8(2/5/1)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 12q24.2-q24.3 1(1/0/0)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 12q24.12 3(3/0/0)
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 12q24.32 1(0/1/0)
PLA2G1B phospholipase A2, group IB (pancreas) 12q24.31 4(1/3/0)
CIT citron rho-interacting serine/threonine kinase 12q24.23 2(1/1/0)
KRT75 keratin 75, type II 12q13.13 1(0/1/0)
IGF1 insulin-like growth factor 1 (somatomedin C) 12q23.2 1(1/0/0)
KRT3 keratin 3, type II 12q13.13 1(1/0/0)
CSRNP2 cysteine-serine-rich nuclear protein 2 12q13.11-q13.12 1(0/1/0)
CUX2 cut-like homeobox 2 12q24.12 3(1/2/0)
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 12q14.1 1(0/1/0)
DUSP6 dual specificity phosphatase 6 12q22-q23 5(3/2/0)
IFT81 intraflagellar transport 81 12q24.13 1(0/0/1)
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 12q13 1(0/0/1)
SCN8A sodium channel, voltage gated, type VIII alpha subunit 12q13.1 1(1/0/0)
LMBR1L limb development membrane protein 1-like 12q13.12 1(0/0/1)
RSRC2 arginine/serine-rich coiled-coil 2 12q24.31 2(1/1/0)
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 12q24.2 2(1/1/0)
GRIP1 glutamate receptor interacting protein 1 12q13.13 1(1/0/0)
CMKLR1 chemokine-like receptor 1 12q23.3 1(0/1/0)
PMCH pro-melanin-concentrating hormone 12q23.2 1(1/0/0)
CCDC65 coiled-coil domain containing 65 12q13.12 1(0/1/0)
HCAR3 hydroxycarboxylic acid receptor 3 12q24.31 1(0/1/0)
IFNG interferon, gamma 12q14 2(2/0/0)
DAO D-amino-acid oxidase 12q24.11 5(1/4/0)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 12q23 1(0/1/0)
TSPAN8 tetraspanin 8 12q14.1-q21.1 2(1/0/1)
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 12q24 9(2/7/0)
SBNO1 strawberry notch homolog 1 (Drosophila) 12q24.31 1(0/1/0)
TPH2 tryptophan hydroxylase 2 12q15 13(10/3/0)
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 12q24.31 1(0/1/0)
RFX4 regulatory factor X, 4 (influences HLA class II expression) 12q24 2(1/1/0)
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 12q24.31 1(1/0/0)
TUBA1B tubulin, alpha 1b 12q13.12 1(1/0/0)
CRY1 cryptochrome circadian clock 1 12q23-q24.1 2(1/1/0)
PAWR PRKC, apoptosis, WT1, regulator 12q21.2 1(0/1/0)
CLIP1 CAP-GLY domain containing linker protein 1 12q24.3 1(0/1/0)
FAM109A family with sequence similarity 109, member A 12q24.12 1(1/0/0)
ALG10B ALG10B, alpha-1,2-glucosyltransferase 12q12 1(0/1/0)
HCAR2 hydroxycarboxylic acid receptor 2 12q24.31 1(0/1/0)
NCOR2 nuclear receptor corepressor 2 12q24 1(0/1/0)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 12q24.31 1(0/1/0)
CCDC92 coiled-coil domain containing 92 12q24.31 1(1/0/0)
NUP107 nucleoporin 107kDa 12q14 1(1/0/0)
KNTC1 kinetochore associated 1 12q24.31 1(0/1/0)
TIMELESS timeless circadian clock 12q13.3 3(0/3/0)
LINC00939 long intergenic non-protein coding RNA 939 12q24.32 1(0/0/1)
NTS neurotensin 12q21.31 1(0/1/0)

View in gBrowse

Region: chr12:38200000..133851895 View in gBrowse
View in gBrowse