Gene Report

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Basic Info

Approved Symbol	SBNO1
Symbol Alias	MOP3, FLJ10701, FLJ10833, Sno
Approved Name	strawberry notch homolog 1 (Drosophila)
Previous Name	sno, strawberry notch homolog 1 (Drosophila)
Location	12q24.31
Position	chr12:123289109-123364843, -1
External Links	HGNC: 22973 Entrez Gene: 55206 Ensembl: ENSG00000139697 UCSC: uc010tap.2
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Shink, E.,2005(a)	Other variant: SBNO1_GC22E16A	We found no polymorphisms associated with bipolar disorder in this gene.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0003674	molecular_function	molecular function	ND	24
GO:0006355	regulation of transcription, DNA-templated	biological process	IEA	62
GO:0008150	biological_process	biological process	ND	24
GO:0005575	cellular_component	cellular component	ND	19

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Variant Name	Variant Type	Location in Gene	No. of Studies (Positive/Negative/Trend)
SBNO1_GC22E16A	point mutation		1 (0/1/0)

Gene related regions (count: 6)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
12q24.3	chr12:120300000-133275309	1 (1/0/0)
Chr 12	chr12:0-133275309	3 (0/3/0)
12q24	chr12:108600000-133275309	4 (1/1/2)
12q23-q24	chr12:95800000-133275309	3 (2/0/1)
12q24.31	chr12:120300000-125400000	1 (1/0/0)
12q	chr12:38200000-133851895	1 (1/0/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr12:123289109..123364843 View in gBrowse