GO Report

Basic Info

ID	GO:0005615
Name	extracellular space
Type	cellular component
No. of Genes in BDgene	85
Source	Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 85)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
INA	internexin neuronal intermediate filament protein, alpha	10q24	1(0/1/0)	IDA[22664934]
CCL2	chemokine (C-C motif) ligand 2	17q11.2-q21.1	3(1/2/0)	IEA
NPPB	natriuretic peptide B	1p36.2	1(1/0/0)	NAS[7601467]
CTSH	cathepsin H	15q25.1	1(0/0/1)	IDA[16502470]
PCSK5	proprotein convertase subtilisin/kexin type 5	9q21.13	1(1/0/0)	IBA; ISS[8940009]
FBN1	fibrillin 1	15q21.1	2(0/2/0)	IDA[20551380]
RSPO4	R-spondin 4	20p13	1(0/1/0)	IBA
SERPINA12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	14q32.13	1(1/0/0)	IBA
NAMPT	nicotinamide phosphoribosyltransferase	7q22.3	1(1/0/0)	IEA
SLIT3	slit homolog 3 (Drosophila)	5q35	1(1/0/0)	IDA[19741192]
GNRH1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	8p21-p11.2	1(0/1/0)	IEA
IGFBP7	insulin-like growth factor binding protein 7	4q12	2(1/1/0)	IDA[20551380]
IL15RA	interleukin 15 receptor, alpha	10p15.1	1(1/0/0)	IEA
NGF	nerve growth factor (beta polypeptide)	1p13.1	2(1/1/0)	IEA
MMP9	matrix metallopeptidase 9	20q13.12	1(1/0/0)	IDA[2251898]
APOB	apolipoprotein B	2p24-p23	1(0/0/1)	ISS[22261194]
WDR60	WD repeat domain 60	7q36.3	1(0/1/0)	IDA[22664934]
GRN	granulin	17q21.32	2(2/0/0)	IEA
APOE	apolipoprotein E	19q13.31	1(1/0/0)	IDA[16502470]
GLDN	gliomedin	15q15.3	1(1/0/0)	IEA
KLK8	kallikrein-related peptidase 8	19q13	1(1/0/0)	ISS
CCK	cholecystokinin	3p22.1	2(0/1/1)	IEA
IL1RN	interleukin 1 receptor antagonist	2q14.2	2(2/0/0)	IDA[10443688]
OLFM3	olfactomedin 3	1p22	1(1/0/0)	IEA
CRHBP	corticotropin releasing hormone binding protein	5q13.3	1(0/1/0)	IDA[1846945]
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	18p11	3(1/2/0)	IEA
PON1	paraoxonase 1	7q21.3	2(2/0/0)	IDA[7638166]
IL10	interleukin 10	1q31-q32	1(0/1/0)	IDA[10443688]
ACE	angiotensin I converting enzyme	17q23.3	5(2/3/0)	IDA[15283675]
UMOD	uromodulin	16p12.3	1(0/0/1)	IEA
CDK13	cyclin-dependent kinase 13	7p14.1	1(1/0/0)	IDA[22664934]
HGFAC	HGF activator	4p16	1(0/0/1)	IEA
CRH	corticotropin releasing hormone	8q13	2(1/1/0)	IDA[18559919]
BDNF	brain-derived neurotrophic factor	11p14.1	37(24/12/1)	IEA
CPB2	carboxypeptidase B2 (plasma)	13q14.11	1(1/0/0)	IEA
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	7q35-q36	1(1/0/0)	IDA[22664934]
EGFR	epidermal growth factor receptor	7p12	1(0/0/1)	NAS[9103388]
CD36	CD36 molecule (thrombospondin receptor)	7q11.2	3(2/1/0)	IDA[16502470]
IGF1	insulin-like growth factor 1 (somatomedin C)	12q23.2	1(1/0/0)	IDA[11404306]
IFNG	interferon, gamma	12q14	2(2/0/0)	IBA
ANXA1	annexin A1	9q21.13	1(0/0/1)	IDA[22664934]
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	3p22.2	2(1/1/0)	IEA
CXCL12	chemokine (C-X-C motif) ligand 12	10q11.1	1(0/0/1)	IEA
SST	somatostatin	3q28	1(0/1/0)	TAS[9437026]
INS	insulin	11p15.5	1(0/1/0)	IDA[9667398]
GPX3	glutathione peroxidase 3	5q33.1	1(1/0/0)	IDA[1897960]
BMP6	bone morphogenetic protein 6	6p24-p23	1(1/0/0)	IBA
GPC5	glypican 5	13q32	1(0/0/1)	IEA
CARTPT	CART prepropeptide	5q13.2	1(0/1/0)	IDA[11711504]; ISS
DLG3	discs, large homolog 3 (Drosophila)	Xq13.1	1(0/1/0)	IDA[22664934]
PNLIPRP1	pancreatic lipase-related protein 1	10q26.12	1(1/0/0)	IDA[19824014]
TNF	tumor necrosis factor	6p21.3	4(2/2/0)	IDA[10443688]
FAM184A	family with sequence similarity 184, member A	6q22.31	1(1/0/0)	IDA[22664934]
OLFM1	olfactomedin 1	9q34.3	1(1/0/0)	IEA
JAM3	junctional adhesion molecule 3	11q25	2(1/1/0)	IDA[20592283]
MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	6p21	1(1/0/0)	IDA[22664934]
FGF12	fibroblast growth factor 12	3q28	1(0/1/0)	TAS[10049777]
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	11q11-q12	1(1/0/0)	IDA[16502470]
CPQ	carboxypeptidase Q	8q22.2	1(0/1/0)	IDA[10206990]
NRG3	neuregulin 3	10q23.1	2(0/2/0)	IBA
SERPINA11	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	14q32.13	1(1/0/0)	IBA
LAMB1	laminin, beta 1	7q22	1(0/0/1)	IDA[10964500]
PLA2G1B	phospholipase A2, group IB (pancreas)	12q24.31	4(1/3/0)	IDA[12860195]
APOD	apolipoprotein D	3q29	1(0/1/0)	IDA[16502470]
CMA1	chymase 1, mast cell	14q12	1(0/0/1)	IBA
MMP3	matrix metallopeptidase 3	11q22.3	1(0/1/0)	TAS[3360803]
FABP3	fatty acid binding protein 3, muscle and heart	1p33-p32	2(1/1/0)	IDA[16502470]
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	1q42.2	1(1/0/0)	IC[1378723]; IDA[16502470]; ISS
CDH13	cadherin 13	16q23.3	3(2/1/0)	IDA[16873731]
IL6	interleukin 6	7p21-p15	1(0/1/0)	IDA[10443688]
RELN	reelin	7q22	3(1/2/0)	ISS
INHBB	inhibin, beta B	2q14.2	1(0/1/0)	IBA
SEMG2	semenogelin II	20q12-q13.1	1(1/0/0)	TAS[1517240]
LGI1	leucine-rich, glioma inactivated 1	10q24	1(0/1/0)	IDA[17067999]
IL1B	interleukin 1, beta	2q14	1(1/0/0)	IDA[12483741]; IMP[3493774]
NRG1	neuregulin 1	8p12	15(10/5/0)	IDA[11389077]
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	3p21.1	2(2/0/0)	IDA[22664934]
S100B	S100 calcium binding protein B	21q22.3	2(1/1/0)	IEA
CBR3	carbonyl reductase 3	21q22.2	1(0/0/1)	IDA[22664934]
ADM	adrenomedullin	11p15.4	1(1/0/0)	IDA[12379507]
CCBE1	collagen and calcium binding EGF domains 1	18q21.32	1(0/1/0)	IDA[24552833]
PCDH15	protocadherin-related 15	10q21.1	4(2/1/1)	IDA[16369489]
MUC4	mucin 4, cell surface associated	3q29	2(0/2/0)	IDA[16502470]
MUC16	mucin 16, cell surface associated	19p13.2	1(0/0/1)	IEA
TFRC	transferrin receptor	3q29	1(0/1/0)	IDA[22664934]