KEGG Pathway Report

Basic Info
ID hsa04540
Name Gap junction
No. of Genes in BDgene  15
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
Gap junction PBA paper Chang, S., 2015 group B i-GSEA4GWAS v2, GenGen FDR=0.166 (B) by i-GSEA4GWAS v2; FDR=0.003 (B) by GenGen

Pathway related genes in BDgene (count: 15)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
EGFR epidermal growth factor receptor 7p12 1(0/0/1)
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Xq23 7(4/3/0)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 22(7/15/0)
TUBA8 tubulin, alpha 8 22q11 2(1/1/0)
ADCY2 adenylate cyclase 2 (brain) 5p15.3 2(1/1/0)
ADCY9 adenylate cyclase 9 16p13.3 2(1/1/0)
GNAS GNAS complex locus 20q13.2-q13.3 1(0/1/0)
DRD2 dopamine receptor D2 11q22-q23 28(8/20/0)
TUBA1B tubulin, alpha 1b 12q13.12 1(1/0/0)
CSNK1D casein kinase 1, delta 17q25 4(2/2/0)
ADCY8 adenylate cyclase 8 (brain) 8q24 4(2/1/1)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3p21.31 1(0/1/0)
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1p36.1 1(0/1/0)
GJA1 gap junction protein, alpha 1, 43kDa 6q22.31 1(1/0/0)
DRD1 dopamine receptor D1 5q34-q35 11(6/5/0)