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KEGG Pathway Report
Basic Info
| ID | hsa04540 |
|---|---|
| Name | Gap junction |
| No. of Genes in BDgene | 15 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Gap junction | PBA paper | Chang, S., 2015 | group B | i-GSEA4GWAS v2, GenGen | FDR=0.166 (B) by i-GSEA4GWAS v2; FDR=0.003 (B) by GenGen |
Pathway related genes in BDgene (count: 15)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| EGFR | epidermal growth factor receptor | 7p12 | 1(0/0/1) |
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | Xq23 | 7(4/3/0) |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 13q14-q21 | 22(7/15/0) |
| TUBA8 | tubulin, alpha 8 | 22q11 | 2(1/1/0) |
| ADCY2 | adenylate cyclase 2 (brain) | 5p15.3 | 2(1/1/0) |
| ADCY9 | adenylate cyclase 9 | 16p13.3 | 2(1/1/0) |
| GNAS | GNAS complex locus | 20q13.2-q13.3 | 1(0/1/0) |
| DRD2 | dopamine receptor D2 | 11q22-q23 | 28(8/20/0) |
| TUBA1B | tubulin, alpha 1b | 12q13.12 | 1(1/0/0) |
| CSNK1D | casein kinase 1, delta | 17q25 | 4(2/2/0) |
| ADCY8 | adenylate cyclase 8 (brain) | 8q24 | 4(2/1/1) |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 3p21.31 | 1(0/1/0) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 1p36.1 | 1(0/1/0) |
| GJA1 | gap junction protein, alpha 1, 43kDa | 6q22.31 | 1(1/0/0) |
| DRD1 | dopamine receptor D1 | 5q34-q35 | 11(6/5/0) |