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BioCarta Pathway Report
Basic Info
| ID | her2Pathway |
|---|---|
| Name | Role of ERBB2 in Signal Transduction and Oncology |
| No. of Genes in BDgene | 7 |
| Source | Pathway by Database Search |
Pathway related genes in BDgene (count: 7)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| EGFR | epidermal growth factor receptor | 7p12 | 1(0/0/1) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| IL6 | interleukin 6 | 7p21-p15 | 1(0/1/0) |
| ESR1 | estrogen receptor 1 | 6q24-q27 | 1(0/1/0) |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 2q33.3-q34 | 2(1/1/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| GRIP1 | glutamate receptor interacting protein 1 | 12q13.13 | 1(1/0/0) |