BDgene

GO Report

Basic Info
ID GO:0007173
Name epidermal growth factor receptor signaling pathway
Type biological process
No. of Genes in BDgene  22
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 22)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
NCK2 NCK adaptor protein 2 2q12 1(1/0/0) TAS[9737977]
FYN FYN proto-oncogene, Src family tyrosine kinase 6q21 1(1/0/0) TAS
AKT1 v-akt murine thymoma viral oncogene homolog 1 14q32.33 3(3/0/0) TAS
FGFR2 fibroblast growth factor receptor 2 10q25.3-q26 2(1/1/0) TAS
ERBB4 erb-b2 receptor tyrosine kinase 4 2q33.3-q34 2(1/1/0) TAS
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 11p15.5-p14 1(0/1/0) TAS[17371240]
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 1(1/0/0) TAS
EGFR epidermal growth factor receptor 7p12 1(0/0/1) IDA[12435727]; TAS
ADCY9 adenylate cyclase 9 16p13.3 2(1/1/0) TAS
ADCY2 adenylate cyclase 2 (brain) 5p15.3 2(1/1/0) TAS
CREB1 cAMP responsive element binding protein 1 2q34 2(1/1/0) TAS
ADAM12 ADAM metallopeptidase domain 12 10q26 1(1/0/0) TAS
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1p36 1(0/0/1) TAS
TNRC6B trinucleotide repeat containing 6B 22q13 1(1/0/0) TAS
GSK3B glycogen synthase kinase 3 beta 3q13.3 8(0/8/0) TAS
FOXO3 forkhead box O3 6q21 1(1/0/0) TAS
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 17q24.2 1(1/0/0) TAS
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1p36.1 1(0/1/0) TAS
PRKCE protein kinase C, epsilon 2p21 1(0/1/0) TAS
NRG1 neuregulin 1 8p12 15(10/5/0) TAS
ADCY8 adenylate cyclase 8 (brain) 8q24 4(2/1/1) TAS
PLCG1 phospholipase C, gamma 1 20q12-q13.1 1(0/1/0) IMP[22454520]; TAS