GO Report

Basic Info
ID GO:0070374
Name positive regulation of ERK1 and ERK2 cascade
Type biological process
No. of Genes in BDgene  14
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 14)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 18p11 3(1/2/0) IDA[23800469]
TLR4 toll-like receptor 4 9q33.1 1(1/0/0) IEA
DCC DCC netrin 1 receptor 18q21.1 2(1/1/0) IEA
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Xq23 7(4/3/0) IDA[19057895]
DRD2 dopamine receptor D2 11q22-q23 28(8/20/0) IEA
TNF tumor necrosis factor 6p21.3 4(2/2/0) NAS[18606301]
EGFR epidermal growth factor receptor 7p12 1(0/0/1) IDA[20551055]
IL6 interleukin 6 7p21-p15 1(0/1/0) IEA
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IDA[10644702]; IMP[12582207]
ADRA1A adrenoceptor alpha 1A 8p21.2 2(0/2/0) ISS
FGFR2 fibroblast growth factor receptor 2 10q25.3-q26 2(1/1/0) ISS
PRKCZ protein kinase C, zeta 1p36.33-p36.2 1(1/0/0) IMP[11035106]
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 22(7/15/0) IDA[19057895]
ERBB4 erb-b2 receptor tyrosine kinase 4 2q33.3-q34 2(1/1/0) IMP[10348342]