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GO Report
Basic Info
| ID | GO:0000165 |
|---|---|
| Name | MAPK cascade |
| Type | biological process |
| No. of Genes in BDgene | 10 |
| Source | Pathway by Database Search |
PBA Result
GO related genes in BDgene (count: 10)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| EGFR | epidermal growth factor receptor | 7p12 | 1(0/0/1) | NAS[15542601] |
| NF1 | neurofibromin 1 | 17q11.2 | 1(1/0/0) | ISS |
| NRG1 | neuregulin 1 | 8p12 | 15(10/5/0) | IEA |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 22q13.33 | 1(0/1/0) | IDA[12244047] |
| INS | insulin | 11p15.5 | 1(0/1/0) | IDA[11278339] |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | 12q24.2 | 2(1/1/0) | TAS[11395482] |
| DOK5 | docking protein 5 | 20q13.2 | 1(1/0/0) | IEA |
| CCL2 | chemokine (C-C motif) ligand 2 | 17q11.2-q21.1 | 3(1/2/0) | IMP[21147091] |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) | IMP[21147091] |
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) | IMP[21147091] |