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KEGG Pathway Report
Basic Info
| ID | hsa04012 |
|---|---|
| Name | ErbB signaling pathway |
| No. of Genes in BDgene | 13 |
| Source | Pathway by Database Search |
Pathway related genes in BDgene (count: 13)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| EGFR | epidermal growth factor receptor | 7p12 | 1(0/0/1) |
| MAPK10 | mitogen-activated protein kinase 10 | 4q22-q23 | 1(0/1/0) |
| PLCG1 | phospholipase C, gamma 1 | 20q12-q13.1 | 1(0/1/0) |
| NRG1 | neuregulin 1 | 8p12 | 15(10/5/0) |
| GSK3B | glycogen synthase kinase 3 beta | 3q13.3 | 8(0/8/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 16q24.1 | 1(0/1/0) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 5q32 | 2(1/1/0) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| NCK2 | NCK adaptor protein 2 | 2q12 | 1(1/0/0) |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 2q33.3-q34 | 2(1/1/0) |
| NRG3 | neuregulin 3 | 10q23.1 | 2(0/2/0) |