Gene Group |
Markers |
Haplotype |
Overlap with SZ |
Statistical Results |
Description |
Result Category |
Reference |
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BRD1
FAM19A5
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rs4468 - D22S1169 - D22S922 - rs132234 |
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P-value = 0.0228 in SZ, P-value = 0.1853 in BD and SZ
P-value = 0.0228 in SZ, P-value = 0.1853 in BD and SZ
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Positive |
Severinsen, J. E., 2006 (b) |
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IL1B
IL1RN
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rs16944 - (IL1RN_intron 2_VNTR) |
C-VNTR(A2) |
Haplotype analysis:Schizophrenia v controls: chi square= 12......
Haplotype analysis:Schizophrenia v controls: chi square= 12.70, global P-value = 0.012; chi square= 9.99, individual P-value = 0.0015; OR = 2.49(95% CI: 1.33 to 4.64).
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Significant association was found in SZ.
Significant association was found in SZ.
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Positive |
Papiol, S.,2004 |
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MCHR1
ADSL
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rs133068 - D22S279 - rs909669; rs133069 - rs133068 - D22S279 - rs909669; rs133070 - rs133069 - rs133068 - D22S279 - rs909669; rs909669 - D22S279 - rs133068 - rs133069 - rs133070; rs909669 - D22S279 - rs133068 - rs133069 - rs133070; rs909669 - D22S279 - rs133068 - rs133069 - rs133070 |
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For markers "rs133068 - D22S279 - rs909669", CLUMP T1 P-val......
For markers "rs133068 - D22S279 - rs909669", CLUMP T1 P-value = 0.4823, CLUMP T4 P-value = 0.3996 in BPD and SZ, CLUMP T1 P-value = 0.099, CLUMP T4 P-value = 0.0353 in SZ; Empirical overall P-value = 0.0319 in BPD and SZ, Empirical overall P-value = 0.0015 in SZ; For markers "rs133069 - rs133068 - D22S279 - rs909669", CLUMP T1 P-value = 0.2672, CLUMP T4 P-value = 0.2064 in BPD and SZ, CLUMP T1 P-value = 0.1481, CLUMP T4 P-value = 0.0495 in SZ; Empirical overall P-value = 0.0591 in BPD and SZ, Empirical overall P-value = 0.0012 in SZ; For markers "rs133070 - rs133069 - rs133068 - D22S279 - rs909669", CLUMP T1 P-value = 0.0059, CLUMP T4 P-value = 0.0031 in BPD and SZ, CLUMP T1 P-value = 0.0156, CLUMP T4 P-value = 0.0054 in SZ; Empirical overall P-value = 0.339 in BPD and SZ, Empirical overall P-value = 0.0497 in SZ; For risk haplotype "rs909669 - D22S279 - rs133068 - rs133069 - rs133070(C-7-C-C-A)", CLUMP P-value = 5E-06 in SZ, P-value = 0.0006 in BPD and SZ; For risk haplotype "rs909669 - D22S279 - rs133068 - rs133069 - rs133070(C-6-C-C-A)", CLUMP P-value = 0.5569 in SZ, P-value = 0.3176 in BPD and SZ; For risk haplotype "rs909669 - D22S279 - rs133068 - rs133069 - rs133070(C-6/7-C-C-A)", CLUMP P-value = 0.0002 in SZ, P-value = 7E-05 in BPD and SZ.
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Similarly, comparing controls to the combined group of case......
Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL.
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Positive |
Severinsen, J. E., 2006 (a) |
|
TSNAX
DISC1
|
rs766288 - rs3738401 - rs2812393 - rs821616; rs766288 - rs821616; rs766288 - rs2812393 |
C-G-G-T; A-G-G-T; C-A |
P-value < 0.05 for markers "rs766288-rs3738401-rs2812393-rs......
P-value < 0.05 for markers "rs766288-rs3738401-rs2812393-rs821616" with haplotype "C-G-G-T" and "A-G-G-T", "rs766288-rs821616" with haplotype "C-A", "A-A" and "A-T", "rs766288-rs2812393" with haplotype "C-C" and "A-G" for SCZ or BPAD&SCZ.
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Several markers among thest two genes were tested associate......
Several markers among thest two genes were tested associated with SCZ or BPAD&SCZ.
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Positive |
Ram Murthy, A., 2012 |
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MAPK8IP2
MOV10L1
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rs715519 - rs2272843; rs715519 - rs2272843 - rs3810971; rs916005 - rs715519 - rs2272843; rs715519 - rs2272843 - rs3810971 - rs137932; rs916005 - rs715519 - rs2272843 - rs3810971 |
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For markers "rs715519 - rs2272843", P-value = 0.6423 in SZ,......
For markers "rs715519 - rs2272843", P-value = 0.6423 in SZ, P-value = 0.7516 in BD and SZ; For markers "rs715519 - rs2272843 - rs3810971", P-value = 0.5626 in SZ, P-value = 0.4568 in BD and SZ; For markers "rs916005 - rs715519 - rs2272843", P-value = 0.9187 in SZ, P-value = 0.9786 in BD and SZ; For markers "rs715519 - rs2272843 - rs3810971 - rs137932", P-value = 0.5239 in SZ, P-value = 0.4123 in BD and SZ; For markers "rs916005 - rs715519 - rs2272843 - rs3810971", P-value = 0.7463 in SZ, P-value = 0.7152 in BD and SZ.
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Negative |
Severinsen, J. E., 2006 (b) |
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MLC1
BRD1
|
rs6010260 - rs138881; rs6010260 - rs138881 - rs138880; rs137931 - rs6010260 - rs138881; rs6010260 - rs138881 - rs138880 - rs2239848; rs137931 - rs6010260 - rs138881 - rs138880; rs137932 - rs137931 - rs6010260 - rs138881 |
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For markers "rs6010260 - rs138881", P-value = 0.3103 in SZ,......
For markers "rs6010260 - rs138881", P-value = 0.3103 in SZ, P-value = 0.4043 in BD and SZ; For markers "rs6010260 - rs138881 - rs138880", P-value = 0.0763 in SZ, P-value = 0.2102 in BD and SZ; For markers "rs137931 - rs6010260 - rs138881", P-value = 0.3326 in SZ, P-value = 0.1926 in BD and SZ; For markers "rs6010260 - rs138881 - rs138880 - rs2239848", P-value = 0.1593 in SZ, P-value = 0.3086 in BD and SZ; For markers "rs137931 - rs6010260 - rs138881 - rs138880", P-value = 0.11 in SZ, P-value = 0.2358 in BD and SZ; For markers "rs137932 - rs137931 - rs6010260 - rs138881", P-value = 0.4183 in SZ, P-value = 0.3061 in BD and SZ.
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Negative |
Severinsen, J. E., 2006 (b) |
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MOV10L1
MLC1
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rs3810971 - rs137932; rs3810971 - rs137932 - rs137931; rs2272843 - rs3810971 - rs137932; rs3810971 - rs137932 - rs137931 - rs6010260; rs2272843 - rs3810971 - rs137932 - rs137931 |
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For markers "rs3810971 - rs137932", P-value = 0.8971 in SZ,......
For markers "rs3810971 - rs137932", P-value = 0.8971 in SZ, P-value = 0.9882 in BD and SZ; For markers "rs3810971 - rs137932 - rs137931", P-value = 0.9061 in SZ, P-value = 0.8355 in BD and SZ; For markers "rs2272843 - rs3810971 - rs137932", P-value = 0.7132 in SZ, P-value = 0.4691 in BD and SZ; For markers "rs3810971 - rs137932 - rs137931 - rs6010260", P-value = 0.1839 in SZ, P-value = 0.2924 in BD and SZ; For markers "rs2272843 - rs3810971 - rs137932 - rs137931", P-value = 0.7849 in SZ, P-value = 0.4295 in BD and SZ.
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Negative |
Severinsen, J. E., 2006 (b) |
|
ST13
MCHR1
|
rs710193 - rs133073; rs710193 - rs133073 - rs133070; rs710193 - rs133073 - rs133070 - rs133069; rs710193 - rs133073 - rs133070 - rs133069 - rs133068; rs1573745 - rs710193 - rs133073; rs1573745 - rs710193 - rs133073 - rs133070; rs1573745 - rs710193 - rs133073 - rs133070 - rs133069 |
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For markers "rs710193 - rs133073 - rs133070 - rs133069", CL......
For markers "rs710193 - rs133073 - rs133070 - rs133069", CLUMP T1 P-value = 0.1755, CLUMP T4 P-value = 0.2417 in BPD and SZ, CLUMP T1 P-value = 0.3957, CLUMP T4 P-value = 0.5862 in SZ; Empirical overall P-value = 0.079 in BPD and SZ, Empirical overall P-value = 0.1069 in SZ. For markers "rs710193 - rs133073 - rs133070 - rs133069 - rs133068", CLUMP T1 P-value = 0.1722, CLUMP T4 P-value = 0.239 in BPD and SZ, CLUMP T1 P-value = 0.3932, CLUMP T4 P-value = 0.5852 in SZ; Empirical overall P-value = 0.1895 in BPD and SZ, Empirical overall P-value = 0.146 in SZ.
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Negative |
Severinsen, J. E., 2006 (a) |
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