BDgene

BD & SZ shared gene-gene interaction from cross-disorder studies

Total result: 8

Gene Group Markers Haplotype Overlap with SZ
Statistical Results Description Result Category Reference
BRD1 FAM19A5 rs4468 - D22S1169 - D22S922 - rs132234
P-value = 0.0228 in SZ, P-value = 0.1853 in BD and SZ P-value = 0.0228 in SZ, P-value = 0.1853 in BD and SZ Positive Severinsen, J. E., 2006 (b)
IL1B IL1RN rs16944 - (IL1RN_intron 2_VNTR) C-VNTR(A2)
Haplotype analysis:Schizophrenia v controls: chi square= 12...... Haplotype analysis:Schizophrenia v controls: chi square= 12.70, global P-value = 0.012; chi square= 9.99, individual P-value = 0.0015; OR = 2.49(95% CI: 1.33 to 4.64). More... Significant association was found in SZ. Significant association was found in SZ. Positive Papiol, S.,2004
MCHR1 ADSL rs133068 - D22S279 - rs909669; rs133069 - rs133068 - D22S279 - rs909669; rs133070 - rs133069 - rs133068 - D22S279 - rs909669; rs909669 - D22S279 - rs133068 - rs133069 - rs133070; rs909669 - D22S279 - rs133068 - rs133069 - rs133070; rs909669 - D22S279 - rs133068 - rs133069 - rs133070
For markers "rs133068 - D22S279 - rs909669", CLUMP T1 P-val...... For markers "rs133068 - D22S279 - rs909669", CLUMP T1 P-value = 0.4823, CLUMP T4 P-value = 0.3996 in BPD and SZ, CLUMP T1 P-value = 0.099, CLUMP T4 P-value = 0.0353 in SZ; Empirical overall P-value = 0.0319 in BPD and SZ, Empirical overall P-value = 0.0015 in SZ; For markers "rs133069 - rs133068 - D22S279 - rs909669", CLUMP T1 P-value = 0.2672, CLUMP T4 P-value = 0.2064 in BPD and SZ, CLUMP T1 P-value = 0.1481, CLUMP T4 P-value = 0.0495 in SZ; Empirical overall P-value = 0.0591 in BPD and SZ, Empirical overall P-value = 0.0012 in SZ; For markers "rs133070 - rs133069 - rs133068 - D22S279 - rs909669", CLUMP T1 P-value = 0.0059, CLUMP T4 P-value = 0.0031 in BPD and SZ, CLUMP T1 P-value = 0.0156, CLUMP T4 P-value = 0.0054 in SZ; Empirical overall P-value = 0.339 in BPD and SZ, Empirical overall P-value = 0.0497 in SZ; For risk haplotype "rs909669 - D22S279 - rs133068 - rs133069 - rs133070(C-7-C-C-A)", CLUMP P-value = 5E-06 in SZ, P-value = 0.0006 in BPD and SZ; For risk haplotype "rs909669 - D22S279 - rs133068 - rs133069 - rs133070(C-6-C-C-A)", CLUMP P-value = 0.5569 in SZ, P-value = 0.3176 in BPD and SZ; For risk haplotype "rs909669 - D22S279 - rs133068 - rs133069 - rs133070(C-6/7-C-C-A)", CLUMP P-value = 0.0002 in SZ, P-value = 7E-05 in BPD and SZ. More... Similarly, comparing controls to the combined group of case...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... Positive Severinsen, J. E., 2006 (a)
TSNAX DISC1 rs766288 - rs3738401 - rs2812393 - rs821616; rs766288 - rs821616; rs766288 - rs2812393 C-G-G-T; A-G-G-T; C-A
P-value < 0.05 for markers "rs766288-rs3738401-rs2812393-rs...... P-value < 0.05 for markers "rs766288-rs3738401-rs2812393-rs821616" with haplotype "C-G-G-T" and "A-G-G-T", "rs766288-rs821616" with haplotype "C-A", "A-A" and "A-T", "rs766288-rs2812393" with haplotype "C-C" and "A-G" for SCZ or BPAD&SCZ. More... Several markers among thest two genes were tested associate...... Several markers among thest two genes were tested associated with SCZ or BPAD&SCZ. More... Positive Ram Murthy, A., 2012
MAPK8IP2 MOV10L1 rs715519 - rs2272843; rs715519 - rs2272843 - rs3810971; rs916005 - rs715519 - rs2272843; rs715519 - rs2272843 - rs3810971 - rs137932; rs916005 - rs715519 - rs2272843 - rs3810971
For markers "rs715519 - rs2272843", P-value = 0.6423 in SZ,...... For markers "rs715519 - rs2272843", P-value = 0.6423 in SZ, P-value = 0.7516 in BD and SZ; For markers "rs715519 - rs2272843 - rs3810971", P-value = 0.5626 in SZ, P-value = 0.4568 in BD and SZ; For markers "rs916005 - rs715519 - rs2272843", P-value = 0.9187 in SZ, P-value = 0.9786 in BD and SZ; For markers "rs715519 - rs2272843 - rs3810971 - rs137932", P-value = 0.5239 in SZ, P-value = 0.4123 in BD and SZ; For markers "rs916005 - rs715519 - rs2272843 - rs3810971", P-value = 0.7463 in SZ, P-value = 0.7152 in BD and SZ. More... Negative Severinsen, J. E., 2006 (b)
MLC1 BRD1 rs6010260 - rs138881; rs6010260 - rs138881 - rs138880; rs137931 - rs6010260 - rs138881; rs6010260 - rs138881 - rs138880 - rs2239848; rs137931 - rs6010260 - rs138881 - rs138880; rs137932 - rs137931 - rs6010260 - rs138881
For markers "rs6010260 - rs138881", P-value = 0.3103 in SZ,...... For markers "rs6010260 - rs138881", P-value = 0.3103 in SZ, P-value = 0.4043 in BD and SZ; For markers "rs6010260 - rs138881 - rs138880", P-value = 0.0763 in SZ, P-value = 0.2102 in BD and SZ; For markers "rs137931 - rs6010260 - rs138881", P-value = 0.3326 in SZ, P-value = 0.1926 in BD and SZ; For markers "rs6010260 - rs138881 - rs138880 - rs2239848", P-value = 0.1593 in SZ, P-value = 0.3086 in BD and SZ; For markers "rs137931 - rs6010260 - rs138881 - rs138880", P-value = 0.11 in SZ, P-value = 0.2358 in BD and SZ; For markers "rs137932 - rs137931 - rs6010260 - rs138881", P-value = 0.4183 in SZ, P-value = 0.3061 in BD and SZ. More... Negative Severinsen, J. E., 2006 (b)
MOV10L1 MLC1 rs3810971 - rs137932; rs3810971 - rs137932 - rs137931; rs2272843 - rs3810971 - rs137932; rs3810971 - rs137932 - rs137931 - rs6010260; rs2272843 - rs3810971 - rs137932 - rs137931
For markers "rs3810971 - rs137932", P-value = 0.8971 in SZ,...... For markers "rs3810971 - rs137932", P-value = 0.8971 in SZ, P-value = 0.9882 in BD and SZ; For markers "rs3810971 - rs137932 - rs137931", P-value = 0.9061 in SZ, P-value = 0.8355 in BD and SZ; For markers "rs2272843 - rs3810971 - rs137932", P-value = 0.7132 in SZ, P-value = 0.4691 in BD and SZ; For markers "rs3810971 - rs137932 - rs137931 - rs6010260", P-value = 0.1839 in SZ, P-value = 0.2924 in BD and SZ; For markers "rs2272843 - rs3810971 - rs137932 - rs137931", P-value = 0.7849 in SZ, P-value = 0.4295 in BD and SZ. More... Negative Severinsen, J. E., 2006 (b)
ST13 MCHR1 rs710193 - rs133073; rs710193 - rs133073 - rs133070; rs710193 - rs133073 - rs133070 - rs133069; rs710193 - rs133073 - rs133070 - rs133069 - rs133068; rs1573745 - rs710193 - rs133073; rs1573745 - rs710193 - rs133073 - rs133070; rs1573745 - rs710193 - rs133073 - rs133070 - rs133069
For markers "rs710193 - rs133073 - rs133070 - rs133069", CL...... For markers "rs710193 - rs133073 - rs133070 - rs133069", CLUMP T1 P-value = 0.1755, CLUMP T4 P-value = 0.2417 in BPD and SZ, CLUMP T1 P-value = 0.3957, CLUMP T4 P-value = 0.5862 in SZ; Empirical overall P-value = 0.079 in BPD and SZ, Empirical overall P-value = 0.1069 in SZ. For markers "rs710193 - rs133073 - rs133070 - rs133069 - rs133068", CLUMP T1 P-value = 0.1722, CLUMP T4 P-value = 0.239 in BPD and SZ, CLUMP T1 P-value = 0.3932, CLUMP T4 P-value = 0.5852 in SZ; Empirical overall P-value = 0.1895 in BPD and SZ, Empirical overall P-value = 0.146 in SZ. More... Negative Severinsen, J. E., 2006 (a)