GO Report

Basic Info

ID	GO:0045202
Name	synapse
Type	cellular component
No. of Genes in BDgene	29
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
SYNAPSE	i-GSEA analysis	Smith, E. N., Mol Psychiatry, 2009	dbGaP GAIN EA	i-GSEA by using i-GSEA4GWAS	P-value<0.001, FDR=0.029	Link in i-GSEA4GWAS
GO: 0045202: synapse	PBA paper	Askland, K.,2009	NIMH	Fisher's exact test	Results given for gene sets with P < 0.01 from the NIMH PBA-CC data

GO related genes in BDgene (count: 29)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	13q32.2	1(1/0/0)	IEA
CHRM2	cholinergic receptor, muscarinic 2	7q35-q36	1(0/1/0)	IBA
OLFM3	olfactomedin 3	1p22	1(1/0/0)	IEA
TENM2	teneurin transmembrane protein 2	5q35	1(0/0/1)	ISS
NOS1	nitric oxide synthase 1 (neuronal)	12q24.22	8(2/5/1)	ISS
CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)	17p13.1	1(1/0/0)	IMP[8872460]
CHRM4	cholinergic receptor, muscarinic 4	11p12-p11.2	1(0/1/0)	IBA
SHISA9	shisa family member 9	16p13.12	1(0/1/0)	ISS
ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	19q13.2	3(2/1/0)	ISS
CTBP2	C-terminal binding protein 2	10q26.13	1(1/0/0)	IEA
LGI1	leucine-rich, glioma inactivated 1	10q24	1(0/1/0)	IEA
PCDH15	protocadherin-related 15	10q21.1	4(2/1/1)	IDA[11487575]
ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	1q23.2	1(1/0/0)	IEA
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	7q21	1(1/0/0)	ISS
CHRM3	cholinergic receptor, muscarinic 3	1q43	1(0/1/0)	IBA
PPP1R9A	protein phosphatase 1, regulatory subunit 9A	7q21.3	1(0/0/1)	IEA
CHRM5	cholinergic receptor, muscarinic 5	15q26	1(0/1/0)	IBA
OLFM1	olfactomedin 1	9q34.3	1(1/0/0)	IEA
CHRM1	cholinergic receptor, muscarinic 1	11q12-q13	1(0/1/0)	IBA
SNAP29	synaptosomal-associated protein, 29kDa	22q11.21	3(1/2/0)	IEA
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	17p13.1	1(1/0/0)	ISS
SYN2	synapsin II	3p25.2	1(0/1/0)	ISS
ADRA2A	adrenoceptor alpha 2A	10q25.2	1(0/1/0)	IEA
CADM2	cell adhesion molecule 2	3p12.2	1(0/1/0)	IEA
CCL2	chemokine (C-C motif) ligand 2	17q11.2-q21.1	3(1/2/0)	IEA
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	9q34.3	3(2/1/0)	ISS
PICK1	protein interacting with PRKCA 1	22q13.1	1(0/1/0)	ISS
VAMP7	vesicle-associated membrane protein 7	Xq28 and Yq12	2(0/2/0)	IEA
GRIN3A	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	9q31.1	1(0/1/0)	IDA[17658481]