BDgene

GO Report

Basic Info
ID GO:0045202
Name synapse
Type cellular component
No. of Genes in BDgene  29
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
SYNAPSE i-GSEA analysis Smith, E. N., Mol Psychiatry, 2009 dbGaP GAIN EA i-GSEA by using i-GSEA4GWAS P-value<0.001, FDR=0.029 Link in i-GSEA4GWAS
GO: 0045202: synapse PBA paper Askland, K.,2009 NIMH Fisher's exact test Results given for gene sets with P < 0.01 from the NIMH PBA-CC data

GO related genes in BDgene (count: 29)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 13q32.2 1(1/0/0) IEA
CHRM2 cholinergic receptor, muscarinic 2 7q35-q36 1(0/1/0) IBA
OLFM3 olfactomedin 3 1p22 1(1/0/0) IEA
TENM2 teneurin transmembrane protein 2 5q35 1(0/0/1) ISS
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 8(2/5/1) ISS
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 17p13.1 1(1/0/0) IMP[8872460]
CHRM4 cholinergic receptor, muscarinic 4 11p12-p11.2 1(0/1/0) IBA
SHISA9 shisa family member 9 16p13.12 1(0/1/0) ISS
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 19q13.2 3(2/1/0) ISS
CTBP2 C-terminal binding protein 2 10q26.13 1(1/0/0) IEA
LGI1 leucine-rich, glioma inactivated 1 10q24 1(0/1/0) IEA
PCDH15 protocadherin-related 15 10q21.1 4(2/1/1) IDA[11487575]
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1q23.2 1(1/0/0) IEA
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(1/0/0) ISS
CHRM3 cholinergic receptor, muscarinic 3 1q43 1(0/1/0) IBA
PPP1R9A protein phosphatase 1, regulatory subunit 9A 7q21.3 1(0/0/1) IEA
CHRM5 cholinergic receptor, muscarinic 5 15q26 1(0/1/0) IBA
OLFM1 olfactomedin 1 9q34.3 1(1/0/0) IEA
CHRM1 cholinergic receptor, muscarinic 1 11q12-q13 1(0/1/0) IBA
SNAP29 synaptosomal-associated protein, 29kDa 22q11.21 3(1/2/0) IEA
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17p13.1 1(1/0/0) ISS
SYN2 synapsin II 3p25.2 1(0/1/0) ISS
ADRA2A adrenoceptor alpha 2A 10q25.2 1(0/1/0) IEA
CADM2 cell adhesion molecule 2 3p12.2 1(0/1/0) IEA
CCL2 chemokine (C-C motif) ligand 2 17q11.2-q21.1 3(1/2/0) IEA
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 9q34.3 3(2/1/0) ISS
PICK1 protein interacting with PRKCA 1 22q13.1 1(0/1/0) ISS
VAMP7 vesicle-associated membrane protein 7 Xq28 and Yq12 2(0/2/0) IEA
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 9q31.1 1(0/1/0) IDA[17658481]