Gene Report

Basic Info
Approved Symbol CHRM5
Approved Name cholinergic receptor, muscarinic 5
Name Alias acetylcholine receptor, muscarinic 5
Location 15q26
Position chr15:33968720-34067457, 1
External Links HGNC: 1954
Entrez Gene: 1133
Ensembl: ENSG00000184984
UCSC: uc001zhk.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shi, J., 2007 SNP: rs2684941, rs2684953, rs2702285, rs4779656, rs499167 no evidence of interaction among these 19 cholinergic genes was found by Allelic Association, Haploview Tests, FITF analysis and FDR correction Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 19)

GO terms by PBA (count: 4)

GO terms by database search (count: 15)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 43)

Literature-origin SNPs (count: 5)

LD-proxies (count: 38)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr15:33968720..34067457 View in gBrowse
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