Gene Report

Basic Info
Approved Symbol THRA
Previous Symbol THRA1, THRA2, ERBA1
Symbol Alias EAR-7.1/EAR-7.2, THRA3, AR7, ERBA, NR1A1
Approved Name thyroid hormone receptor, alpha
Previous Name thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog), "thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)"
Location 17q21.1
Position chr17:40058290-40093867, 1
External Links HGNC: 11796
Entrez Gene: 7067
Ensembl: ENSG00000126351
UCSC: uc002htw.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kripke, D. F.,2009 SNP: rs939348 Significant association was observed in the BP group. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 43)

GO terms by PBA (count: 6)

GO terms by database search (count: 37)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 27)

Related other genetic factors
Gene related SNPs (count: 7)

Literature-origin SNPs (count: 5)

LD-proxies (count: 2)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr17:40058290..40093867 View in gBrowse
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