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GO Report
Basic Info
| ID | GO:0050796 |
|---|---|
| Name | regulation of insulin secretion |
| Type | biological process |
| No. of Genes in BDgene | 24 |
| Source | Pathway by Database Search |
PBA Result
GO related genes in BDgene (count: 24)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CHRM3 | cholinergic receptor, muscarinic 3 | 1q43 | 1(0/1/0) | TAS |
| GNAS | GNAS complex locus | 20q13.2-q13.3 | 1(0/1/0) | TAS |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) | 6p12 | 1(0/1/0) | IMP[15940393] |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 3p14.3 | 1(1/0/0) | TAS |
| PER2 | period circadian clock 2 | 2q37.3 | 7(1/6/0) | ISS |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 1p36.1 | 1(0/1/0) | TAS |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) | 17p13.1 | 1(1/0/0) | TAS |
| HNF4A | hepatocyte nuclear factor 4, alpha | 20q13.12 | 1(1/0/0) | ISS |
| CARTPT | CART prepropeptide | 5q13.2 | 1(0/1/0) | IEA |
| CACNA1E | calcium channel, voltage-dependent, R type, alpha 1E subunit | 1q25.3 | 1(1/0/0) | TAS |
| SNAP25 | synaptosomal-associated protein, 25kDa | 20p12-p11.2 | 2(2/0/0) | TAS[15537656] |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 12p13.3 | 20(17/3/0) | TAS |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 17q24.2 | 1(1/0/0) | TAS |
| CNR1 | cannabinoid receptor 1 (brain) | 6q14-q15 | 5(0/5/0) | IEA |
| ADRA2A | adrenoceptor alpha 2A | 10q25.2 | 1(0/1/0) | TAS |
| INS | insulin | 11p15.5 | 1(0/1/0) | TAS |
| IFNG | interferon, gamma | 12q14 | 2(2/0/0) | IDA[8383325] |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 10q22.2 | 2(1/1/0) | ISS |
| CLOCK | clock circadian regulator | 4q12 | 12(5/7/0) | ISS |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) | IDA[8383325] |
| ADRA2C | adrenoceptor alpha 2C | 4p16.3 | 1(0/1/0) | TAS |
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) | IDA[8383325] |
| SSTR5 | somatostatin receptor 5 | 16p13.3 | 2(1/1/0) | IBA |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 11p15 | 7(5/2/0) | ISS |