GO Report

Basic Info
ID GO:0050796
Name regulation of insulin secretion
Type biological process
No. of Genes in BDgene  24
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 24)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
CHRM3 cholinergic receptor, muscarinic 3 1q43 1(0/1/0) TAS
GNAS GNAS complex locus 20q13.2-q13.3 1(0/1/0) TAS
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(0/1/0) IMP[15940393]
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 3p14.3 1(1/0/0) TAS
PER2 period circadian clock 2 2q37.3 7(1/6/0) ISS
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1p36.1 1(0/1/0) TAS
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17p13.1 1(1/0/0) TAS
HNF4A hepatocyte nuclear factor 4, alpha 20q13.12 1(1/0/0) ISS
CARTPT CART prepropeptide 5q13.2 1(0/1/0) IEA
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1q25.3 1(1/0/0) TAS
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 2(2/0/0) TAS[15537656]
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 20(17/3/0) TAS
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 17q24.2 1(1/0/0) TAS
CNR1 cannabinoid receptor 1 (brain) 6q14-q15 5(0/5/0) IEA
ADRA2A adrenoceptor alpha 2A 10q25.2 1(0/1/0) TAS
INS insulin 11p15.5 1(0/1/0) TAS
IFNG interferon, gamma 12q14 2(2/0/0) IDA[8383325]
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 10q22.2 2(1/1/0) ISS
CLOCK clock circadian regulator 4q12 12(5/7/0) ISS
TNF tumor necrosis factor 6p21.3 4(2/2/0) IDA[8383325]
ADRA2C adrenoceptor alpha 2C 4p16.3 1(0/1/0) TAS
IL1B interleukin 1, beta 2q14 1(1/0/0) IDA[8383325]
SSTR5 somatostatin receptor 5 16p13.3 2(1/1/0) IBA
ARNTL aryl hydrocarbon receptor nuclear translocator-like 11p15 7(5/2/0) ISS