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GO Report
Basic Info
| ID | GO:0004674 |
|---|---|
| Name | protein serine/threonine kinase activity |
| Type | molecular function |
| No. of Genes in BDgene | 27 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| GO: 0004674: protein serine/threonine kinase act. | PBA paper | Askland, K.,2009 | WTCCC Frequentist genotypic | Fisher's exact test | P < 0.05 from the WTCCC PBAs |
GO related genes in BDgene (count: 27)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| STK24 | serine/threonine kinase 24 | 13q31.2-q32.3 | 2(1/1/0) | IDA[16314523] |
| PRKCZ | protein kinase C, zeta | 1p36.33-p36.2 | 1(1/0/0) | EXP; IDA[15069075] |
| NEK7 | NIMA-related kinase 7 | 1q31.3 | 2(0/1/1) | IBA; ISS |
| TAOK2 | TAO kinase 2 | 16p11.2 | 1(0/1/0) | IDA[10660600] |
| CSNK1E | casein kinase 1, epsilon | 22q13.1 | 5(1/3/1) | IDA[15917222]; TAS[7797465] |
| EIF2AK4 | eukaryotic translation initiation factor 2 alpha kinase 4 | 15q13.3 | 1(0/1/0) | ISS |
| STK39 | serine threonine kinase 39 | 2q24.3 | 2(0/2/0) | IDA[24393035] |
| CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 20p13 | 2(0/2/0) | IDA[12700239]; IMP[11035045]; TAS[2174700] |
| PSKH1 | protein serine kinase H1 | 16q22.1 | 1(1/0/0) | IEA |
| SLK | STE20-like kinase | 10q25.1 | 1(0/0/1) | IDA[18239682] |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 14q32.32 | 1(0/1/0) | ISS |
| VRK2 | vaccinia related kinase 2 | 2p16.1 | 1(0/1/0) | IDA[14645249] |
| NEK4 | NIMA-related kinase 4 | 3p21.1 | 1(1/0/0) | ISS |
| TRIO | trio Rho guanine nucleotide exchange factor | 5p14-p15.1 | 1(0/1/0) | IEA |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) | IEA |
| CIT | citron rho-interacting serine/threonine kinase | 12q24.23 | 2(1/1/0) | ISS[9792683] |
| AURKB | aurora kinase B | 17p13.1 | 1(1/0/0) | IDA[22724069] |
| PRKCE | protein kinase C, epsilon | 2p21 | 1(0/1/0) | IDA[15695813] |
| RIOK1 | RIO kinase 1 | 6p24.3 | 2(1/0/1) | IEA |
| NEK5 | NIMA-related kinase 5 | 13q14.2 | 1(0/1/0) | IBA |
| GSK3B | glycogen synthase kinase 3 beta | 3q13.3 | 8(0/8/0) | IDA[11035810]; ISS; TAS |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 5q32 | 2(1/1/0) | ISS |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) | IDA[10102273]; TAS[21432781] |
| CSNK1D | casein kinase 1, delta | 17q25 | 4(2/2/0) | IBA |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 1p36 | 1(0/0/1) | EXP; IDA[15467718]; TAS |
| BCR | breakpoint cluster region | 22q11 | 2(1/1/0) | IEA |
| TNK2 | tyrosine kinase, non-receptor, 2 | 3q29 | 1(0/1/0) | IEA |