Gene Report

Basic Info
Approved Symbol CSNK2A1
Approved Name casein kinase 2, alpha 1 polypeptide
Location 20p13
Position chr20:473591-543821, -1
External Links HGNC: 2457
Entrez Gene: 1457
Ensembl: ENSG00000101266
UCSC: uc002wdx.1
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Byrne, E. M., 2014 P-value=0.20. Gene-based tests show no significant association between this gene and BD. Negative Comment on Study
Mansour, H. A.,2009 Gene-based tests:X<sup>2</sup>=5.274, P-value = 0.136 in dominant model, X<sup>2</sup>=2.372, P-value = 0.551 in recessive model, X<sup>2</sup>=1.527, P-value = 0.687 in additive model in BPI. No significant association was observed using neither single SNP-based analyses nor gene-based tests in BPI. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 26)

GO terms by PBA (count: 4)

GO terms by database search (count: 22)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 11)

Gene related interactors from protein-protein interactions data in HPRD (count: 161)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr20:473591..543821 View in gBrowse
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