GO Report

Basic Info
ID GO:0007417
Name central nervous system development
Type biological process
No. of Genes in BDgene  21
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
GO: 0007417: central nervous system development PBA paper Askland, K.,2009 NIMH Fisher's exact test Results given for gene sets with P < 0.01 from the NIMH PBA-BP data
CENTRAL NERVOUS SYSTEM DEVELOPMENT i-GSEA analysis From NIMH Pritzker Neuropsychiatric Disorders Research Consortium i-GSEA by using i-GSEA4GWAS P-value< 0.001, FDR=0.040666666 Link in i-GSEA4GWAS

GO related genes in BDgene (count: 21)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
GPR124 adhesion G protein-coupled receptor A2 8p11.22 0 ISS
TPP1 tripeptidyl peptidase I 11p15.4 1(1/0/0) IBA
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 3p12.3 1(0/1/0) NAS[9458045]
NPTX1 neuronal pentraxin I 17q25.3 2(1/1/0) TAS[8884281]
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 5q14.2 1(0/1/0) IEA
NPAS2 neuronal PAS domain protein 2 2q11.2 5(3/2/0) TAS[9012850]
RELN reelin 7q22 3(1/2/0) ISS
PAX8 paired box 8 2q13 1(0/0/1) IEP[15494458]
NMUR2 neuromedin U receptor 2 5q33.1 1(0/1/0) IEP[10899166]
FYN FYN proto-oncogene, Src family tyrosine kinase 6q21 1(1/0/0) IBA
MBP myelin basic protein 18q23 1(1/0/0) TAS[2434243]
POU6F2 POU class 6 homeobox 2 7p14.1 1(1/0/0) TAS[8601806]
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 4p12 2(2/0/0) IEA
PARK2 parkin RBR E3 ubiquitin protein ligase 6q25.2-q27 1(1/0/0) TAS[9560156]
DRP2 dystrophin related protein 2 Xq22 1(1/0/0) TAS[8640231]
S100B S100 calcium binding protein B 21q22.3 2(1/1/0) TAS[8202493]
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 15q25.1 1(0/1/0) ISS
SNTG2 syntrophin, gamma 2 2p25 1(0/0/1) TAS[10747910]
NCAN neurocan 19p12 1(1/0/0) IBA
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 7q31.3 1(1/0/0) TAS[8387522]
CNTN6 contactin 6 3p26.3 1(1/0/0) TAS[9486763]