Gene Report

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Basic Info

Approved Symbol	CNTN6
Symbol Alias	NB-3
Approved Name	contactin 6
Name Alias	neural adhesion molecule
Location	3p26.3
Position	chr3:1092576-1404217, 1
External Links	HGNC: 2176 Entrez Gene: 27255 Ensembl: ENSG00000134115 UCSC: uc003boz.4
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Noor A., 2014		Selected stringent CNV related to this gene is validated by qPCR from BD case data.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005886	plasma membrane	cellular component	IEA	360
GO:0007155	cell adhesion	biological process	IEA	42
GO:0007411	axon guidance	biological process	TAS	60
GO:0007417	central nervous system development	biological process	TAS[9486763]	21

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0031225	anchored component of membrane	cellular component	IEA	11
GO:0007219	Notch signaling pathway	biological process	IEA	14

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 3)

ID	Location	Size	Band	Type
CNV_Abdul Noor[2014]_2	chr3:1294698-1449128 (NCBI Build 36/hg18)	154000	3p26.3	deletion
CNV_Zhang[2009]_71	chr3:832458-1403398 (Affymetrix SNP 6.0 array reference genome)	570940		Singleton deletions
CNV_Abdul Noor[2014]_25	chr3:38411-3305438 (NCBI Build 36/hg18)	3	3p26.3	deletion

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 3	chr3:0-198295559	2 (0/2/0)
3p24-p26	chr3:0-30800000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr3:1092576..1404217 View in gBrowse