BDgene

Gene Report

Basic Info
Approved Symbol MBP
Approved Name myelin basic protein
Location 18q23
Position chr18:76978827-77133683, -1
External Links HGNC: 6925
Entrez Gene: 4155
Ensembl: ENSG00000197971
UCSC: uc010xfd.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0010. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 22)

GO terms by PBA (count: 5)

GO terms by database search (count: 17)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 40)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 2)


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Region: chr18:76978827..77133683 View in gBrowse
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