Gene Report

Basic Info
Approved Symbol ROBO2
Symbol Alias KIAA1568
Approved Name roundabout, axon guidance receptor, homolog 2 (Drosophila)
Previous Name roundabout (axon guidance receptor, Drosophila) homolog 2
Location 3p12.3
Position chr3:75906695-77649964, 1
External Links HGNC: 10250
Entrez Gene: 6092
Ensembl: ENSG00000185008
UCSC: uc003dpy.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kuo, P. H., 2014 SNP: rs13322211 Gene-based P-value (allelic model) =0.1065, P-value (additive model) =0.0878. ROBO2 stood out for their potential biological plausibility to be associated with bipolar illness. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 21)

GO terms by PBA (count: 4)

GO terms by database search (count: 17)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 25)

Literature-origin SNPs (count: 1)

LD-proxies (count: 24)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr3:75906695..77649964 View in gBrowse
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