Study Report

Basic Info
Citation Kripke, D. F., C. M. Nievergelt, et al. (2009). Circadian polymorphisms associated with affective disorders. J Circadian Rhythms 7: 2.
Disease Type Bipolar Disorder & Major Depressive Disorder
Study Design family-based
Study Type Candidate-gene association study
Sample Size Bipolar probands and families:444 nuclear families including 561 affected offspring(bipolar type 1 disorder, bipolar type 2 disorder, and schizoaffective (bipolar type) patients);Bipolar probands and the morningness-eveningness quantitative trait:130 unrelated research volunteers;Unipolar major depression affected sibling pairs:298 individuals in 149 families (89 concordant and 60 discordant sibpairs);Sleep Clinic sample:360 patients suffered from depression
SNP/Region/Marker Size 260 SNPs
Predominant Ethnicity Caucasian

Detail Info

SNPs reported by this study for BD (count: 17)

Genes reported by this study for BD (count: 8)