BDgene

SNP Report

Basic Info
Name rs2314339 dbSNP Ensembl
Location chr17:40096959 - 40096959(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.294129
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000264637, ENST00000394121, ENST00000450525, ENST00000584985); intron_variant(ENST00000246672)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kripke, D. F.,2009 T/C TDT: In BP: OR=0.612, CHISQ=13.71, P-value = 0.0002, empiric...... TDT: In BP: OR=0.612, CHISQ=13.71, P-value = 0.0002, empirical P-value = 0.0005, corrected empirical P-value = 0.0338 More... Significant association was observed in the BP group. Significant association was observed in the BP group. Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
THRA thyroid hormone receptor, alpha 17q21.1 1(1/0/0)
NR1D1 nuclear receptor subfamily 1, group D, member 1 17q11.2 6(2/4/0)

SNPs in LD with rs2314339 (count: 1) View in gBrowse (chr17:40096407..40096959 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)