BDgene

SNP Report

Basic Info
Name rs2269457 dbSNP Ensembl
Location chr17:40098436 - 40098436(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.396765
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000264637, ENST00000394121, ENST00000584985); intron_variant(ENST00000246672)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kripke, D. F.,2009 G/A TDT: In BP: OR=0.799, CHISQ=4.803, P-value = 0.0284, empiric...... TDT: In BP: OR=0.799, CHISQ=4.803, P-value = 0.0284, empirical P-value = 0.0292, corrected empirical P-value = 0.9861 More... Significant association was observed in the BP group. Significant association was observed in the BP group. Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
THRA thyroid hormone receptor, alpha 17q21.1 1(1/0/0)
NR1D1 nuclear receptor subfamily 1, group D, member 1 17q11.2 6(2/4/0)

SNPs in LD with rs2269457 (count: 0) View in gBrowse (chr17:40098436..40098436 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)