SNP Report

Basic Info

Name	rs2585405 dbSNP Ensembl
Location	chr17:8143454 - 8143454(1)
Variant Alleles	C/G
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.228235
Functional Annotation	downstream_gene_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant. Polyphen Annotation: benign(ENST00000317276, ENST00000581082) SIFT Annotation: tolerated(ENST00000317276, ENST00000581082)
Consequence to Transcript	downstream_gene_variant(ENST00000354903, ENST00000577424, ENST00000578223, ENST00000578950, ENST00000579203, ENST00000581395, ENST00000583559, ENST00000585095, ENST00000614952); intron_variant(ENST00000582719); missense_variant(ENST00000317276, ENST00000581082); NMD_transcript_variant(ENST00000582719); non_coding_transcript_exon_variant(ENST00000578089); non_coding_transcript_variant(ENST00000578089); upstream_gene_variant(ENST00000579098, ENST00000583677, ENST00000585284)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kripke, D. F.,2009	G/C		TDT: In BP: OR=0.735, CHISQ=4.734, P-value = 0.0296, empiric...... TDT: In BP: OR=0.735, CHISQ=4.734, P-value = 0.0296, empirical P-value = 0.0457, corrected empirical P-value = 0.9881 More...	Significant association was observed in the BP group. Significant association was observed in the BP group.	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PER1	period circadian clock 1	17p13.1	5(2/3/0)
PGAP3	post-GPI attachment to proteins 3	17q21.2	Mapped by LD-proxy

SNPs in LD with rs2585405 (count: 0) View in gBrowse (chr17:8143454..8143454 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)