BDgene

Study Report

Basic Info
Reference
Citation Maheshwari, M., J. Shi, et al. (2009). Common and rare variants of DAOA in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 150B(7): 960-966.
Disease Type Bipolar Disorder
Study Design case-control and family-based
Study Type Candidate-gene association study
Sample Size Common SNP Association Tests:376 parent-offspring trios (parents plus one affected child) consisted of 335 bipolar disorder type I patients(BP-I) and 41 schizoaffective disorder bipolar type(SAB) patients;19 families with 146 samples in a subset of CNG pedigrees(52 BP-I and 20 BP-II);Rare Variant Association Test:555 unrelated bipolar patients(531 BP-I and 24 SAB) and 564 unrelated control subjects
SNP/Region/Marker Size 38 SNPs for Common SNP Association Test,8 SNPs for STatistical Explanation,53 SNPs for Rare Variant Association Test
Predominant Ethnicity Caucasian
Gender male/female: 157/219 in Common SNP Association Tests samples, in BD patients and 267/198 in controls;19/33 in BPI and 4/16 in BPII in a subset of CNG pedigrees;228/327 in BP and 282/282 in controls in Rare Variant Association Test samples

Detail Info

SNPs reported by this study for BD (count: 39)

Genes reported by this study for BD (count: 1)