SNP Report

Basic Info

Name	rs778336 dbSNP Ensembl
Location	chr13:105504165 - 105504165(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.336861
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000448407); non_coding_transcript_variant(ENST00000448407)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soronen, P.,2011	T/C		For BD, allele, P-value = 0.2718 For BD, allele, P-value = 0.2718	No significant association was observed. No significant association was observed.	Negative
Maheshwari, M.,2009	C/T		TDT: Raw TDT P-value = 0.449, Adaptive permutation corrected...... TDT: Raw TDT P-value = 0.449, Adaptive permutation corrected P-value = 0.625 More...	No significant allelic association with BP was found No significant allelic association with BP was found	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DAOA-AS1	DAOA antisense RNA 1	13q33.2	Mapped by Literature SNP
DAOA	D-amino acid oxidase activator	13q33.2	21(13/7/1)

SNPs in LD with rs778336 (count: 2) View in gBrowse (chr13:105504165..105536776 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs778281			0.918[CEU]
rs778297			0.918[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soronen, P.,2011	For MDD, allele, P-value = 0.0406;For Mood, allele, P-value = 0.031, OR=0.8072, P-value(perm)=0.769	Significant association was found.	Positive