Region Report

Basic Info

Region Name	22q11.2
Chromosome Position	chr22:17400000-25500000
No. of Studies (Positive/Negative/Trend)	2(0/2/0)

Region related studies (count: 2)

Reference	Markers	Statistical Values	Author Comments	Result Category
Turecki, G.,2000	X82209_CAG/CAA repeats	Association analysis: Monte Carlo approach, P-value > 0.05 Association analysis: Monte Carlo approach, P-value > 0.05	No significant association was observed in BD. No significant association was observed in BD.	Negative
Savitz, J.,2007	D22S421, D22S315, D22S1164	Combined Merlin-SimWalk2 Analyses: For marker D22S421, NPL-p...... Combined Merlin-SimWalk2 Analyses: For marker D22S421, NPL-pair = 0.04, P-value = 0.9106; For marker D22S315, NPL-pair = 0.1, P-value = 0.8029; For marker D22S1164, NPL-pair = 0.04, P-value = 0.9124 More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 20)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RTN4R	reticulon 4 receptor	22q11	1(0/1/0)
COMT	catechol-O-methyltransferase	22q11.21	28(14/14/0)
UBE2L3	ubiquitin-conjugating enzyme E2L 3	22q11.2	1(0/1/0)
CABIN1	calcineurin binding protein 1	22q11.23	1(0/0/1)
ZDHHC8	zinc finger, DHHC-type containing 8	22q11.21	1(0/1/0)
DGCR8	DGCR8 microprocessor complex subunit	22q11.2	2(1/0/1)
TUBA8	tubulin, alpha 8	22q11	2(1/1/0)
DGCR6	DiGeorge syndrome critical region gene 6	22q11.21	1(0/1/0)
PRODH	proline dehydrogenase (oxidase) 1	22q11.2	4(0/4/0)
MED15	mediator complex subunit 15	22q11.2	1(0/1/0)
GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	22q11.1-q11.2	1(1/0/0)
DGCR14	DiGeorge syndrome critical region gene 14	22q11.21	1(0/1/0)
GSC2	goosecoid homeobox 2	22q11.21	1(0/1/0)
BCR	breakpoint cluster region	22q11	2(1/1/0)
PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	22q11.21	3(1/2/0)
ZNF74	zinc finger protein 74	22q11.2	1(0/1/0)
DGCR6L	DiGeorge syndrome critical region gene 6-like	22q11.21	1(0/1/0)
GNB1L	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	22q11.2	1(1/0/0)
UFD1L	ubiquitin fusion degradation 1 like (yeast)	22q11.2	1(0/1/0)
SNAP29	synaptosomal-associated protein, 29kDa	22q11.21	3(1/2/0)

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Region: chr22:17400000..25500000 View in gBrowse