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KEGG Pathway Report
Basic Info
| ID | hsa04660 |
|---|---|
| Name | T cell receptor signaling pathway |
| No. of Genes in BDgene | 13 |
| Source | Pathway by Database Search |
Pathway related genes in BDgene (count: 13)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| PLCG1 | phospholipase C, gamma 1 | 20q12-q13.1 | 1(0/1/0) |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 8p21.3 | 1(0/1/0) |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 2q33 | 2(1/1/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 10q22.2 | 2(1/1/0) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| NCK2 | NCK adaptor protein 2 | 2q12 | 1(1/0/0) |
| IL10 | interleukin 10 | 1q31-q32 | 1(0/1/0) |
| IFNG | interferon, gamma | 12q14 | 2(2/0/0) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 6q21 | 1(1/0/0) |
| ITK | IL2-inducible T-cell kinase | 5q31-q32 | 1(1/0/0) |