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GO Report
Basic Info
| ID | GO:0050852 |
|---|---|
| Name | T cell receptor signaling pathway |
| Type | biological process |
| No. of Genes in BDgene | 9 |
| Source | Pathway by Database Search |
PBA Result
GO related genes in BDgene (count: 9)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| PLCG1 | phospholipase C, gamma 1 | 20q12-q13.1 | 1(0/1/0) | TAS |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 6q25.1 | 1(0/0/1) | TAS |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 16q24.1 | 1(0/1/0) | ISS |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 6q21 | 1(1/0/0) | IDA[7722293] |
| ITK | IL2-inducible T-cell kinase | 5q31-q32 | 1(1/0/0) | IBA; ISS; TAS |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit | 12q13 | 1(0/0/1) | IEA |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 1p31 | 3(1/2/0) | IMP[17404263] |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 5q12 | 1(0/1/0) | IMP[17404263] |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) | TAS |