SNP Report

Basic Info

Name	rs2282751 dbSNP Ensembl
Location	chr3:50254353 - 50254353(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.464058
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000266027, ENST00000313601, ENST00000422163, ENST00000440628, ENST00000441156, ENST00000446079, ENST00000451956, ENST00000468422, ENST00000490122, ENST00000491100); NMD_transcript_variant(ENST00000441156, ENST00000446079); non_coding_transcript_variant(ENST00000468422, ENST00000490122, ENST00000491100); upstream_gene_variant(ENST00000492383)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McDonald, M. L.,2012			chi square test:OR(95%CI) = 1.2(1.1â€“1.4),P-value = 0.0061 ...... chi square test:OR(95%CI) = 1.2(1.1â€“1.4),P-value = 0.0061 for BD-I More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	3p21.31	1(0/1/0)

SNPs in LD with rs2282751 (count: 1) View in gBrowse (chr3:50254353..50262685 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs4141060		downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.901[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)