KEGG Pathway Report

Basic Info
ID hsa04730
Name Long-term depression
No. of Genes in BDgene  15
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
Long-term depression PBA paper Chang, S., 2015 group B i-GSEA4GWAS v2, GenGen FDR=0.1464 (B) by i-GSEA4GWAS v2; FDR=0.058 (B) by GenGen

Pathway related genes in BDgene (count: 15)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 22q13.1 2(1/1/0)
GRIA1 glutamate receptor, ionotropic, AMPA 1 5q33 2(2/0/0)
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 8(2/5/1)
NOS3 nitric oxide synthase 3 (endothelial cell) 7q36 2(1/1/0)
CRHR1 corticotropin releasing hormone receptor 1 17q21.31 4(2/2/0)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(1/0/0)
GRIA3 glutamate receptor, ionotropic, AMPA 3 Xq25 1(0/1/0)
GNAS GNAS complex locus 20q13.2-q13.3 1(0/1/0)
PLA2G1B phospholipase A2, group IB (pancreas) 12q24.31 4(1/3/0)
IGF1 insulin-like growth factor 1 (somatomedin C) 12q23.2 1(1/0/0)
CRH corticotropin releasing hormone 8q13 2(1/1/0)
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 4p16.1 2(1/1/0)
GNA12 guanine nucleotide binding protein (G protein) alpha 12 7p22.3 1(1/0/0)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3p21.31 1(0/1/0)
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 8p21.2 1(0/1/0)