BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

Search Gene with Disease Search Gene1 with Disease

Region Report

Basic Info

Region Name	11p15
Chromosome Position	chr11:0-22000000
No. of Studies (Positive/Negative/Trend)	5(0/4/1)

Region related studies (count: 5)

Reference	Markers	Statistical Values	Author Comments	Result Category
Nievergelt, C. M., 2006	D11S4116, D11S4170	LOD = -6.63 for marker D11S4116 at Theta = 0 for the narrow...... LOD = -6.63 for marker D11S4116 at Theta = 0 for the narrow diagnostic and AR50 genetic model, LOD = -3.49 at Theta = 0.05 for the narrow diagnostic and AR50 genetic model, LOD = -1.93 at Theta = 0.1 for the narrow diagnostic and AR50 genetic model; LOD = -5.64 for marker D11S4170 at Theta = 0 for the narrow diagnostic and AR50 genetic model, LOD = -2.09 at Theta = 0.05 for the narrow diagnostic and AD50 genetic model, LOD = -0.69 at Theta = 0.1 for the narrow diagnostic and AD50 genetic model More...		Negative
Liu, J.,2003	D11S2362	Multipoint ASP results: LOD = 1.44, Model BP3 Multipoint ASP results: LOD = 1.44, Model BP3	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
De bruyn, A.,1994	TH - DRD4 - HARS - INS		No significant linkage was found in this region No significant linkage was found in this region	Negative
Service, S.,2006	rs960647	Two point parametric linkage analysis: LOD = 1.4141 Two point parametric linkage analysis: LOD = 1.4141	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
McInnis, M. G.,2003(a)	D11S1923	Linkage analysis: model H, Conditional NPL = 2.7, P-value = ...... Linkage analysis: model H, Conditional NPL = 2.7, P-value = 0.002 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 14)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)
CCKBR	cholecystokinin B receptor	11p15.4	1(1/0/0)
TPH1	tryptophan hydroxylase 1	11p15.3-p14	14(5/9/0)
TPP1	tripeptidyl peptidase I	11p15.4	1(1/0/0)
PIK3C2A	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	11p15.5-p14	1(0/1/0)
ADM	adrenomedullin	11p15.4	1(1/0/0)
TH	tyrosine hydroxylase	11p15.5	16(4/12/0)
SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 5	11p15.1	1(0/1/0)
DRD4	dopamine receptor D4	11p15.5	13(1/12/0)
CHRNA10	cholinergic receptor, nicotinic, alpha 10 (neuronal)	11p15.5	1(0/1/0)
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	11p15.4	1(0/1/0)
INS	insulin	11p15.5	1(0/1/0)
ZDHHC13	zinc finger, DHHC-type containing 13	11p15.1	1(0/0/1)
NAV2	neuron navigator 2	11p15.1	1(1/0/0)

View in gBrowse

Region: chr11:0..22000000 View in gBrowse